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| Name | Class |
|---|---|
| National Mango Board | OTHER |
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Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins. Mango extract has been reported to protect against photo-aging of the skin in an animal model exposed to UVB radiation, reducing the length of wrinkles and increasing collagen bundles. Beta-carotene and other carotenoids are known to provide skin protection from sunlight, but other compounds in mangos, may also be important in reducing oxidative damage in aging skin.
We have recently completed a pilot study showing a clear trend in skin wrinkle reduction when postmenopausal women consumed 85g of Ataulfo mangos, four times per week for 16 weeks. To confirm and extend these results, a larger study is proposed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mango | Experimental | 85g mango, 4x/week |
|
| No Mango | No Intervention | No mango intake |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Food | Other | 85g mango, 4x/week |
|
| Measure | Description | Time Frame |
|---|---|---|
| Wrinkles | Wrinkle score measured by Facial Image Analysis System | week 20 |
| Measure | Description | Time Frame |
|---|---|---|
| Facial Hydration | Moisture measured by MoistureMeterSC | week 20 |
| Facial Redness | Redness measured by Facial Image Analysis System | week 20 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Raja Sivamani, MD, MS, AP | Contact | 9165241216 | raja.sivamani@integrativeskinresearch.com | |
| Vivien Fam, PhD, RDN | Contact | 5307605968 | vivien@integrativeskinresearch.com |
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| ID | Term |
|---|---|
| D005502 | Food |
| ID | Term |
|---|---|
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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Healthy postmenopausal women aged 50 - 70, Fitzpatrick skin type I, II, or III
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| Facial Elasticity | measured by Cutometer | week 20 |
| Gut microbiome | analyze for changes in gut microbiome diversity measures (Shannon Diversity) | week 20 |
| Gut microbiome | Analyze for the relative abundance of short chain fatty acid producing bacteria | week 20 |