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| Name | Class |
|---|---|
| Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London | UNKNOWN |
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To develop and train a convolutional neural network to detect and characterize disease severity of inflammatory bowel disease during endoscopy
To develop and train a Convolutional Neural Network to detect and characterize disease severity in inflammatory bowel disease during endoscopy. This initiative will inevitably establish a high-quality large image database. Our secondary study aims are therefore to use the images we collect to advance the field of deep learning and computer aided diagnosis in inflammatory bowel disease by establishing an image database. This will involve developing a framework combining deep learning and computer vision algorithms. The ultimate aim is to use the image database to produce high impact research outcomes and training resources leading to an improvement in the quality of endoscopy performed, reduce inter-observer variability in disease assessment and a reduction in missed bowel cancer rates and associated mortality.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Main group | Patients with/suspected Inflammatory Bowel Disease attending for an endoscopic procedure | ||
| Control | Patients without Inflammatory Bowel disease attending for an endoscopic procedure |
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| Measure | Description | Time Frame |
|---|---|---|
| To develop and train a convolutional neural network to detect and characterise disease severity of inflammatory bowel disease during endoscopy | To develop and train a convolutional neural network to detect and characterise disease severity of inflammatory bowel disease during endoscopy | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| a) To explore whether Artificial Intelligence can predict response to IBD therapies | To explore whether Artificial Intelligence can predict response to IBD therapies | 5 years |
| b) To develop an endoscopic image repository to advance training and standardisation in endoscopic detection and characterisation of IBD. |
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Inclusion Criteria:
Exclusion Criteria:
• Any patient under the age of 16
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Inflammatory Bowel Disease (IBD) affects at least one in 250 people of the UK population and the prevalence is rising.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shaji Sebastian | Contact | 01482 816764 | shaji.sebastian@hey.nhs.uk | |
| Laurence Lovat | Contact | 02076799606 | l.lovat@ucl.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Shaji Sebastian | Hull University Teaching Hospitals NHS Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hull Royal Infirmary | Recruiting | Hull | East Yorkshire | HU3 2JZ | United Kingdom |
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| ID | Term |
|---|---|
| D003424 | Crohn Disease |
| ID | Term |
|---|---|
| D015212 | Inflammatory Bowel Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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b) To develop an endoscopic image repository to advance training and standardisation |
| 5 years |
| c) To develop and assess methodologies for training and quality assurance of IBD diagnostic endoscopy | To develop and assess methodologies for training and quality assurance of IBD | 5 years |
| d) To evaluate comparisons in endoscopic image interpretation between endoscopist's | To evaluate comparisons in endoscopic image interpretation between endoscopist's | 5 years |
| e) To develop deep learning algorithms and computer vision techniques to allow for automated measurement of quality metrics in endoscopy for IBD | To develop deep learning algorithms and computer vision techniques to allow for automated measurement of quality metrics in endoscopy for IBD | 5 years |
| f) To create a future robust research platform to ensure the above objectives are continuously developed as novel imaging techniques emerge over time. | To create a future robust research platform to ensure the above objectives are continuously developed as novel imaging techniques emerge over time. | 5 years |
| D007410 | Intestinal Diseases |