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Many treatments like acupuncture, manipulative therapy and pharmacological therapy have been proposed to alleviate symptoms associated with dysmenorrhea. However, no study has previously compared lumbar spine manipulation to pharmacological therapy in the treatment of primary dysmenorrhea.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lumbar spine manipulation | Experimental | Application of lumbar spine manipulation by a physical therapist. |
|
| Lumbar spine manipulation plus pharmacological therapy | Active Comparator | Application of lumbar spine manipulation by a physical therapist along with pharmacological therapy. |
|
| Pharmacological therapy | Active Comparator | Application of pharmacological therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lumbar spine manipulation | Other | Lumbar spine manipulation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain intensity | Pain intensity measured with a visual analogue scale | Change from baseline at 3 days |
| Measure | Description | Time Frame |
|---|---|---|
| Pressure pain threshold measured in tibialis malleolus | Pressure pain threshold measured with an algometer in tibialis malleolus | Change from baseline at 3 days |
| Pressure pain threshold measured in peroneal malleolus |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Adelina Jazmin Castillo-Sanchez | Puebla City | 72000 | Mexico | |||
| Ruben Fernandez-Matias |
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| ID | Term |
|---|---|
| D012601 | Scopolamine |
| D007052 | Ibuprofen |
| ID | Term |
|---|---|
| D012602 | Scopolamine Derivatives |
| D014326 | Tropanes |
| D053961 | Azabicyclo Compounds |
| D001372 | Aza Compounds |
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| Hyoscine and Ibuprofen | Drug | hyoscine (20 mg) and ibuprofen (400 mg) administered by oral via. |
|
Pressure pain threshold measured with an algometer in peroneal malleolus
| Change from baseline at 3 days |
| Low-back related disability | Low-back related disability measured with the Oswestry Disability Index | Change from baseline at 1 month |
| Anxiety and depression | Anxiety and depression measured with the Hospital Anxiety and Depression Scale | Change from baseline at 1 month |
| Alcalá de Henares |
| 28805 |
| Spain |
| D009930 |
| Organic Chemicals |
| D001533 | Belladonna Alkaloids |
| D012991 | Solanaceous Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D019086 | Bridged Bicyclo Compounds, Heterocyclic |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D010666 | Phenylpropionates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |