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This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for postsurgical pain in adults.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgery patients | Patients who undergo various common surgical procedures |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiothoracic surgery | Procedure | Cardiac & large intrathoracic vessels, respiratory, thoracic, mediastinal & diaphragmatic procedures |
|
| Measure | Description | Time Frame |
|---|---|---|
| Chronic post surgical pain | Pain related to the surgical procedure measured as average pain intensity on rest or movement using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable and/or average pain interference using 11-point NRS among any one of seven short-form Brief Pain Inventory items (general activity, mood, walking ability, normal work (including housework), relations with other people, sleep, enjoyment of life) in the past one week, where 0=pain does not interfere and 10=pain completely interferes. | 3 months post surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Acute post surgical pain | Acute post surgical pain intensity in the first 3 hours after surgery measured as pain at rest using 11-point numeric rating scale (NRS; 0-10) where 0=no pain and 10=worst pain imaginable. | First 3 hours after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients who undergo surgery meeting inclusion and exclusion criteria
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| Name | Affiliation | Role |
|---|---|---|
| Lone Nikolajsen, DMSc | Aarhus University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aarhus University Hospital | Aarhus N | 8200 | Denmark | |||
| Silkeborg Regional Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39297720 | Derived | Papadomanolakis-Pakis N, Haroutounian S, Sorensen JK, Runge C, Brix LD, Christiansen CF, Nikolajsen L. Development and internal validation of a clinical risk tool to predict chronic postsurgical pain in adults: a prospective multicentre cohort study. Pain. 2025 Mar 1;166(3):667-679. doi: 10.1097/j.pain.0000000000003405. Epub 2024 Sep 18. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D015412 | Mastectomy, Segmental |
| D013505 | Digestive System Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| ID | Term |
|---|---|
| D008408 | Mastectomy |
| D013514 | Surgical Procedures, Operative |
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| Breast surgery | Procedure | Breast resections & mastectomies |
|
| Gastrointestinal surgery | Procedure | Digestive & spleen |
|
| Genitourinary surgery | Procedure | Urinary tract, genital & retroperitoneal tissue |
|
| Orthopaedic surgery | Procedure | Back & neck, shoulder & upper arm, hip & thigh, knees & lower leg |
|
| Silkeborg |
| Denmark |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |