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An investigation of the neuropsychological processes underlying ethical decision making.
This study will investigate the influence of reward sensitivity on cheating behavior via experimental manipulation of reward sensitivity using testosterone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| testosterone | Experimental | 7mg testosterone propionate |
|
| placebo | Placebo Comparator | 125 mg 0.5% cholorbutanol, 50mg saline, pH5 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| testosterone propionate | Drug | 1mg/0.1mL solution, to be administered intranasally |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measure of ethical behavior - Cheating rate defined as the Average number of 'heads' coin flips participants claim to have obtained | drug administration following by behavioral outcome. Specifically, participants will have the opportunity to predict the outcome of a series of coin flips. To obtain a measure of ethical behavior, participants will have the opportunity to cheat by over-reporting their prediction accuracy. | 90 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robert A Josephs, PhD | University of Texas at Austin | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Robert Josephs | Austin | Texas | 78712-1050 | United States |
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| ID | Term |
|---|---|
| D000987 | Antisocial Personality Disorder |
| ID | Term |
|---|---|
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D043343 | Testosterone Propionate |
| D012965 | Sodium Chloride |
| ID | Term |
|---|---|
| D013739 | Testosterone |
| D000737 | Androstenols |
| D000736 | Androstenes |
| D000731 | Androstanes |
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| 0.5% cholorbutanol, saline | Drug | 125 mg 0.5% cholorbutanol, 50mg saline |
|
| D013256 |
| Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D045165 | Testosterone Congeners |
| D012739 | Gonadal Steroid Hormones |
| D042341 | Gonadal Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
| D017670 | Sodium Compounds |