Radial Artery Puncture Hemostasis Study

Radial Artery Puncture Hemostasis: Physical, Biological and Chemical Methods

RAPHE is an open label randomized clinical trial to assess physical, biological and chemical methods of radial artery puncture hemostasis following coronary catheterization.

A total of 600 subjects will be randomized in a 1:1:1 fashion to either the StatSeal, Axiostat or TR Band hemostasis devices.

Follow-up of the subject will take place 60 days after the index procedure.

Inclusion Criteria:

• Coronary angiogram planned from a radial artery approach
• Use of 5, 6 or 7 French sheaths

Exclusion Criteria:

• Radial artery diameter <1.8 mm as measured via ultrasound
• Established peripheral arterial disease
• Known autoimmune illness
• Hemodynamic instability
• Pregnant or nursing
• Condition following resuscitation