Using CGM for Evaluating Effects of Food on Glucose Regulation in Healthy Humans

Development of Methodology for Use of Continuous Blood Glucose Measurements When Evaluating Meal Effects on Glucose Regulation - a Pilot Trial

The specific goal of this pilot study is to evaluate if it is possible to detect a statistical difference in postprandial glycemia after meals served with and without a drink previously shown to reduce postprandial glycemia by about 25%. A third drink, with a new recipe, is also included for comparisons. Six participants will carry continuous blood glucose monitors for 10 days and follow a specific meal schedule. The data from this study will form the basis for forming hypothesis of future studies as well as make appropriate calculations of statistical power.

Inclusion Criteria:

• BMI 25-29.9 kg/m^2
• HOMA-IR < 2.5
• Fasting glucose < 6.1 mmol/L
• Stable weight since 3 months
• Access to iPhone with Bluetooth 4.0 and iOS 13 or later

Exclusion Criteria:

• Diabetes
• Pharmacological treatment known to interfer with metabolism
• Antibiotics treatment the latest 3 months
• Vegetarian/Vegan diet
• Use of tobacco
• Pregnancy or breast-feeding