Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation

Effectiveness of Different Membrane Applications (Perforated Polytetrafluroethylene (PTFE) vs. Perforated PTFE+ Collagen Membrane) in Vertical Ridge Augmentation - Randomized Clinical Trial

This randomized clinical trial (RCT) study investigates if there is any difference in absolute vertical bone gain between perforated dense-polytetrafluroethylene (d-PTFE) mesh vs perforated d-PTFE mesh covered with a native collagen membrane.

The primary endpoint is absolute vertical bone gain. The secondary endpoints are regeneration rate, complications rate, and pseudoperiosteum formation.

Inclusion Criteria:

1. Partially edentulous patients requiring vertical and horizontal ridge augmentation
2. patients agrees with conditions of the study and sign consent

Exclusion Criteria:

• Insufficient oral hygiene
• Smoking
• Alcohol or Drug abuse
• acute local or systemic infections
• uncontrolled diabetes or other metabolic disease
• severe hepatic or renal disfunction
• autoimmune disease
• radiotherapy in the last 5 years
• patients receiving immunosuppressive therapy