Prospective Study of White Blood Cells | NCT04838171

Studies
Prospective Study of White Blood Cells

NCT04838171

Sponsor

Quell Therapeutics Limited

Status

Recruiting

Last Update Posted

Jan 21, 2026Actual

Enrollment

10Estimated

Phase

Not provided

Conditions

Autoimmune Diseases
Inflammation
Rejection; Transplant, Liver

Interventions

White blood cell and blood collection

Countries

United Kingdom

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jan 2026

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 24, 2021Actual

Primary Completion Date

Dec 31, 2029Estimated

Completion Date

Jan 2030Estimated

First Submitted Date

Apr 1, 2021

First Submission Date that Met QC Criteria

Apr 6, 2021

First Posted Date

Apr 8, 2021Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 16, 2026

Last Update Posted Date

Jan 21, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

The purpose of this study is to investigate white blood cells from volunteering donors to support the development of engineered regulatory T cell therapies.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

10Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Specimen collection to support development of engineering Treg			Other: White blood cell and blood collection

Interventions

Name	Type	Description	Arm Group Labels	Other Names
White blood cell and blood collection	Other	Mononucleocytes will be collected via apheresis	Specimen collection to support development of engineering Treg

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
WBC characterisation to support the development of engineered regulatory T cells.	number, type and function of white blood cells in healthy controls and in patients	5 years

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

No additional inclusion/ exclusion criteria will be applied by Quell other than those specified by the consenting institutions.

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

Volunteers willing to provide white blood cells for research.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Gareth Wright	Contact	+4(0)2070969012		contact@quell-tx.com

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Quell Investigator Site 01	Recruiting	London			United Kingdom

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D001327	Autoimmune Diseases
D007249	Inflammation
D012059	Rejection, Psychology

Ancestor Terms

ID	Term
D007154	Immune System Diseases
D010335	Pathologic Processes
D013568	Pathological Conditions, Signs and Symptoms
D012919	Social Behavior

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D007958	Leukocyte Count

Ancestor Terms

ID	Term
D001772	Blood Cell Count
D002452	Cell Count
D003584	Cytological Techniques
D019411	Clinical Laboratory Techniques

Browse Leaves

Not provided

Browse Branches

Not provided