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The aim of the study is to investigate Work of Breathing of a person in simulated avalanche snow and consequent use of the measured data for judging which one of three simulated scenarios are alike while increasing hypercapnia in the simulated avalanche snow.
The study is a part of a university diploma thesis aimed at studying physiological conditions and development of breathing parameters of a person breathing in the simulated avalanche snow. The Investigator is measuring Work of Breathing in three scenarios: a) 2L air pocket, b) 2L air pocket with resistance compensation and c) no air pocket. The investigator hypothesize that the Work of Breathing during compensation of air pocket will be alike with no air pocket scenario, thus proving significance of the resistance reduction for survival. The aim of the study is to investigate the effect of Work of Breathing on gas exchange in subjects breathing into the simulated avalanche snow scenarios.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Wet Perlite, 2L air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of wet perlite with 2L air pocket |
|
| Wet Perlite 2L air pocket with resistance compensation | Experimental | Breathing in the simulated avalanche snow. Breathing into model of wet perlite 2L air pocket with resistance compensation |
|
| Wet Perlite, no air pocket | Experimental | Breathing in the simulated avalanche snow. Breathing into model of wet perlite with no air pocket |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| extreme hypercapnia induced by ventilation insufficiency | Other | extreme hypercapnia |
|
| Measure | Description | Time Frame |
|---|---|---|
| The length of breathing | Time to termination of the breathing experiment due to the decision of the tested subject, or determined by high end-tidal carbon dioxide value or by the order by the clinician assessing the health status of the subjects. | Continuously within up to 7 minute interval from the beginning of the breathing experiment |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Karel RoubÃk, PhD | Czech Technical University in Prague, FBMI | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Czech Technical University, Faculty of Biomedical Engineering | Kladno | 272 01 | Czechia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26666523 | Background | Roubik K, Sieger L, Sykora K. Work of Breathing into Snow in the Presence versus Absence of an Artificial Air Pocket Affects Hypoxia and Hypercapnia of a Victim Covered with Avalanche Snow: A Randomized Double Blind Crossover Study. PLoS One. 2015 Dec 14;10(12):e0144332. doi: 10.1371/journal.pone.0144332. eCollection 2015. |
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| ID | Term |
|---|---|
| D006935 | Hypercapnia |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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