Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Single-center, randomized, parallel-group, controlled, open-label study. The aim of the study was to evaluate the effects of an exercise training program intervention of different intensities (high intensity versus low-moderate intensity) on blood pressure reduction as a complementary strategy in hypertensive individuals being treated with at least one antihypertensive drug.
All participants included in the study were referred by their primary care physicians, who prescribed physical exercise as a healthy lifestyle intervention added to the antihypertensive regimens in the framework of the "ACTIVA-Murcia Program".
Participants in the HIT and LMIT groups followed the same physical training program, with the only difference being the intensity of the training. The program included two phases of physical exercise lasting 12 weeks and 16 weeks, respectively, separated by a 7-week rest period, which coincided with a holiday period. The times of both phases were not equal in terms of duration, since it is a community physical exercise program established by the Region of Murcia, and does not depend on the researchers.
The program was developed by graduates in Physical Activity and Sport Sciences, who were in charge of teaching the exercises and supervised each training session.
Participants assigned to the HIT and LMIT groups were given guidelines to continue physical exercise during the 7-week rest period, while participants in the control group were offered to participate in the program after the study.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High intensity training (HIT) group | Experimental | The HIT group performed the exercises with loads at 80-90% of HRF. |
|
| Low-moderate intensity training (LMIT) group | Experimental | The HIT group performed the exercises with the loads at 50-70% of the HRF |
|
| No training group | Placebo Comparator | They did not perform any type of programmed physical exercise during the study. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Therapeutic physical exercise | Other | The physical training program was carried out 3 days a week in 1-hour sessions focused on basic endurance exercises (global body activities), strength (specific muscle region activities) and flexibility. Intensity was be determined by Maximum Heart Rate (HRF). |
| Measure | Description | Time Frame |
|---|---|---|
| Ambulatory blood pressure monitoring | Blood pressure is measured with a holter | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Measure | Description | Time Frame |
|---|---|---|
| Systolic blood pressure | Blood pressure is measured with a holter | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Diastolic blood pressure |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Catholic University of Murcia | Murcia | 30107 | Spain |
Not provided
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001519 | Behavior |
Not provided
Not provided
A single-center, randomized, parallel-group, controlled, and open-label study was conducted.
Not provided
Not provided
Not provided
Not provided
|
| No physical exercise | Other | No programmed physical exercise |
|
Blood pressure is measured with a holter
| Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Mean blood pressure | Blood pressure is measured with a holter | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Pulse pressure | Blood pressure is measured with a holter | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Lipid profile | Blood samples | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Antihypertensive medication | Record of medication and dosage | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Lipid lowering medication | Record of medication and dosage | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Control of dietary intake | Diet source | A nutritional registry will be carried out. The nutritional intake of three days in two periods will be collected. One record at the beginning and another at the end, that is, six days. |
| Muscle function | Isokinetic dynamometry. | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Balance | Force platform Kistler | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Aerobic function | Modified Balke-Ware protocol on a rolling mat | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |
| Framingham tables by category | Physicians Global Assessment to measure cardiovascular risk | Measurements will be taken at baseline and 12 weeks (phase 1) and at baseline and 16 weeks (phase 2) |