Recurrent Urinary Tract Infections and the Microbiome

Is PCR Amplification More Sensitive Than Urine Cultures in Diagnosing Urinary Tract Infections in Patients With Recurrent Bladder Infections?

The primary objective is to determine if polymerase chain reaction (PCR) (UTIP™) is more sensitive in identifying urinary tract infections (UTI's) than standard urine cultures.

Inclusion Criteria:

• 18 y/o-90 y/o
• Able to consent
• Female
• Group A only: Recurrent UTI (2 UTIs in 6 months)
• Group B only: No history of recurrent UTIs

Exclusion Criteria:

• Pregnant
• Pelvic radiation
• Urinary retention (>200 ml residual)
• Greater than Stage 2 prolapse
• Renal calculi
• Immunosuppressed
• Neurologic disorder with significant bladder impairment
• No current UTI via dip stick