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The Swan-Ganz catheter is the gold standard to measure cardiac output during liver transplantation surgery. This is an invasive hemodynamic monitoring system.
The VenArt Cardiac Output (Mespere LifeSciences, Waterloo, Canada) is a new, innovative and non-invasive device that permits hemodynamic monitoring.
With a software based on Fick's principle it is able to calculate cardiac output, cardiac index and continuous cardiac output.
The hypothesis of this study is to investigate the precision and accuracy of this method versus the standard of care during liver transplantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| OLTx | Liver insufficiency patients undergoing transplantation surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VEnaRt Cardiac Output | Device | Every patient is monitored during liver transplantation with VEnaRt Cardiac Output versus Swan-Ganz Catheter |
|
| Measure | Description | Time Frame |
|---|---|---|
| Precision of VenArt Cardiac Output cardiac output, cardiac index and continuous cardiac output measures | Evaluate the precision of VenArt Cardiac Output cardiac output, cardiac index and continuous cardiac output versus the pulmonary catheter in patients undergoing liver transplantation | During surgery |
| Accuracy of VenArt Cardiac Output cardiac output, cardiac index and continuous cardiac output measures | Evaluate the accuracy of VenArt Cardiac Output cardiac output, cardiac index and continuous cardiac output versus the pulmonary catheter in patients undergoing liver transplantation | During surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation | Analyze the VenArt Cardiac Output and Swan-Ganz catheter statistical correlation of cardiac output and cardiac index measures | During surgery |
| Concordance | Analyze the VenArt Cardiac Output and Swan-Ganz catheter statistical concordance of cardiac output and cardiac index measures |
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Inclusion Criteria:
Exclusion Criteria:
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All the patients undergoing liver transplant at our institution
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anesthesiology and Intensive Care Clinic - Department of Medicine - ASUIUD | Udine | 33100 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18581507 | Background | De Wolf AM. Pulmonary artery catheter: rest in peace? Not just quite yet.. Liver Transpl. 2008 Jul;14(7):917-8. doi: 10.1002/lt.21543. No abstract available. | |
| 26052376 | Background | Rudnick MR, Marchi LD, Plotkin JS. Hemodynamic monitoring during liver transplantation: A state of the art review. World J Hepatol. 2015 Jun 8;7(10):1302-11. doi: 10.4254/wjh.v7.i10.1302. |
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| ID | Term |
|---|---|
| D002303 | Cardiac Output, Low |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| During surgery |
| Time of device positioning | Evaluate the time necessary to position the VenArt Cardiac Output and Swan-Ganz catheter | During surgery |
| Device positioning complications | Evaluate the complication during the VenArt Cardiac Output and Swan-Ganz catheter positioning. | During surgery |
| 20634793 | Background | Cecconi M, Dawson D, Casaretti R, Grounds RM, Rhodes A. A prospective study of the accuracy and precision of continuous cardiac output monitoring devices as compared to intermittent thermodilution. Minerva Anestesiol. 2010 Dec;76(12):1010-7. Epub 2010 Jul 16. |
| 2868172 | Background | Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;1(8476):307-10. |
| 18946716 | Background | Weinbroum AA, Biderman P, Soffer D, Klausner JM, Szold O. Reliability of cardiac output calculation by the fick principle and central venous oxygen saturation in emergency conditions. J Clin Monit Comput. 2008 Oct;22(5):361-6. doi: 10.1007/s10877-008-9143-y. Epub 2008 Oct 23. |
| 12578081 | Background | Critchley LA, Critchley JA. A meta-analysis of studies using bias and precision statistics to compare cardiac output measurement techniques. J Clin Monit Comput. 1999 Feb;15(2):85-91. doi: 10.1023/a:1009982611386. |
| 20736431 | Background | Critchley LA, Lee A, Ho AM. A critical review of the ability of continuous cardiac output monitors to measure trends in cardiac output. Anesth Analg. 2010 Nov;111(5):1180-92. doi: 10.1213/ANE.0b013e3181f08a5b. Epub 2010 Aug 24. |
| 29725794 | Background | Vetrugno L, Bignami E, Barbariol F, Langiano N, De Lorenzo F, Matellon C, Menegoz G, Della Rocca G. Cardiac output measurement in liver transplantation patients using pulmonary and transpulmonary thermodilution: a comparative study. J Clin Monit Comput. 2019 Apr;33(2):223-231. doi: 10.1007/s10877-018-0149-9. Epub 2018 May 3. |