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| ID | Type | Description | Link |
|---|---|---|---|
| 2021-A00748-33 | Other Identifier | ID-RCB |
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Malignant pleural mesothelioma (MPM) is a rare pleural cancer, which could be primary or secondary to an asbestos exposure. To enhance our knowledge of this rare disease, an exploration of genetic and tumor mechanism is mandatory. One of the principal difficulty is to harvest sufficient tumour pieces to perform multi-omics analysis. The goal of the SCITH-MESO study is to harvest larges pieces of tumour during a routine surgical procedure of MPM diagnosis by mean of pleural biopsies during VATS surgery. Operating samples will increase a tissue bank collection (CRB).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA | All patient with suspected malignant pleural mesothelioma requiring surgical biopsy after validation in oncologic multidisciplinary board will be included. During a standardized routine procedure of pleural biopsy by mean of general anesthesia and video thoracoscopic approach, 3 - 5 biopsies are realized. During this procedure, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA | Genetic | All patient with suspected malignant pleural mesothelioma requiring surgical biopsy after validation in oncologic multidisciplinary board will be included. During a standardized routine procedure of pleural biopsy by mean of general anesthesia and video thoracoscopic approach, 3 - 5 biopsies are realized. During this procedure, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques). |
| Measure | Description | Time Frame |
|---|---|---|
| For patients with MPM, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques). | For patients with MPM, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques). | day 1 (day of chirurgie) |
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Inclusion Criteria:
Exclusion Criteria:
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all patient with suspected malignant pleural mesothelioma requiring surgical biopsy for diagnosis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jean-Michel MAURY, MD | Contact | 04.72.35.75.90 | +33 | jean-michel.maury@chu-lyon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Département de chirurgie thoracique | Recruiting | Bron | 69677 | France |
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| ID | Term |
|---|---|
| D000086002 | Mesothelioma, Malignant |
| ID | Term |
|---|---|
| D008654 | Mesothelioma |
| D000236 | Adenoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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pleural samples of malignant pleural mesothelioma
|
| D009369 |
| Neoplasms |
| D018301 | Neoplasms, Mesothelial |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D010997 | Pleural Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |