Pilot Study of reSET-O to Treatment-as-usual in Acute Care Settings

Pilot Study of reSET-O to Treatment-as-usual in Acute Care Settings

This randomized controlled pilot study will evaluate feasibility, acceptability, and potential efficacy of an app, reSET-O, for patients being started on buprenorphine in acute care settings.

This randomized controlled pilot study will enroll 60 participants, who will be randomly assigned to a treatment as usual (TAU) group or a reSET-O+TAU group after being started on buprenorphine in acute care settings (e.g., emergency department) and referred to community treatment. Study enrollment will last for 3 months after discharge from the acute care setting. Participants in the reSET-O+TAU group will be provided with the reSET-O app and will be encouraged to engage with the app for the 3 months following discharge from the acute care unit. The app works as an extension of cognitive behavioral therapy, providing psychoeducation related to opioid use disorder. All participants will be assessed at study intake and every month during the 3-month intervention.

Inclusion Criteria:

• 18-65 years old
• Opioid use disorder
• Eligible for buprenorphine treatment
• Has reSET-O compatible mobile device

Exclusion Criteria:

• Pregnancy
• Significant psychiatric comorbidity