Intrathecal Morphine for Radical Robot Assisted Prostatectomy (TORNADO)

Intrathecal Morphine Compared to Intravenous Tramadol and Transversus Abdominal Plane Block for Catheter Related Bladder Discomfort Syndrome

investigators aim to compare the efficacy of intrathecal morphine, intravenous tramadol and transversus abdominis plane block in the treatment of catheter related bladder discomfort syndrome in patients scheduled for robotic assisted laparoscopic prostatectomy

patients scheduled for robot assisted laparoscopic prostatectomy will be treated depending on the belonging group. In the morphine group patients will receive intrathecal morphine 0,15 mg; in the transversus abdominis plane block patients will receive ropivacaine 80 mg; in the tramadol group patients will receive intravenous continuous infusion of tramadol 400 mg for the first 24 hours postoperatively. All data will be collected in the post anesthesia room and in the ward until the first post operative day.

Inclusion Criteria:

• all patients scheduled for robotic assisted laparoscopic prostatectomy

Exclusion Criteria:

• coagulation disorders and platelet dysfunction for spinal arm
• obesity for transversus abdominis plane block arm
• left ventricular ejection fraction < 30%, end-stage renal disease and neurological disorders for all groups