RCT Comparing OAGB and Long Limb Roux Gastric Bypass

A Multicentre Randomized Controlled Trial Comparing Outcome of Laparoscopic One-anastomosis Gastric Bypass and Laparoscopic Long Biliopancreatic Limb Roux Gastric Bypass for Treatment of Morbid Obesity.

A prospective multicenter randomized controlled trial to compare the outcomes of one-anastomosis gastric bypass to long biliary limb Roux gastric bypass.

We plan to enroll up to 500 patients from three different clinics in Estonia. Outcomes are excess weight loss %, impact on type 2 diabetes, hypertension, hyperlipidemia and obstructive sleep apnea.

Other outcomes are nutritional deficiencies, occurrence of reflux disease and impact on quality of life.

There are planned outpatient visits 1, 5 and 10 years after the surgery to measure the impacts.

There are a lot of studies comparing OAGB to standard Roux gastric bypass but non comparing it to long biliary limb gastric bypass.

Inclusion Criteria:

• BMI over 35 and obesity related disease
• BMI over 40
• age between 18-60 years
• agrees to participate in the study

Exclusion Criteria:

• age under 18 years or over 60 years
• abundant adhesions discovered during the surgery
• active upper gastrointestinal ulcer disease
• prior bariatric surgery
• active symptomatic reflux disease
• active psychiatric disease (eg psychosis)