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The purpose of this research is to establish the normal range of diameter and distensibility of pylorus and the fasting and postprandial antro-pyloric motility in healthy adults.
An Endoflip catheter will be placed through the mouth into the stomach in order to measure distal antral contractile activity and pyloric diameter and distensibility during fasting and after the ingestion of a standard meal
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| observational study of gastric and pyloric motor function measured with Endoflip | observational study of gastric and pyloric motor function measured with Endoflip during fasting and postprandial periods There is NO intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endoflip measurement of gastric and pyloric function | Diagnostic Test | Endoflip device to measure gastric and pyloric functions |
|
| Measure | Description | Time Frame |
|---|---|---|
| fasting and postprandial pyloric diameter | Change in Pyloric diameter will be measured during fasting and postprandial using Endoflip | 1 hour prior to meal and 1 hour following standardized meal |
| fasting and postprandial pyloric distensibility index | Change in Pyloric distensibility index will be measured during fasting and postprandial using Endoflip | 1 hour prior to meal and 1 hour following standardized meal |
| fasting and postprandial distal antral motility index | Change in distal antral motility index will be measured during fasting and postprandial using Endoflip | 1 hour prior to meal and 1 hour following standardized meal |
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Inclusion Criteria:
Exclusion Criteria:
equal number of males and females will be recruited for this study in up to 45 adults
healthy adults between the ages of 18 and 65 with body mass indices between 18 and 35 kilograms/meter squared will be recruited for this study
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| Name | Affiliation | Role |
|---|---|---|
| Michael Camilleri, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Michael Camilleri | Rochester | Minnesota | 55905 | United States |
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| Label | URL |
|---|---|
| Mayo Clinic Clinical Trials | View source |
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