Study Evaluating the Effect of Isonatremic Dialysis Treatment in Chronic Kidney Disease Patients on Dialysis

Evaluation of the Effect of Isonatremic (vs Conventional) Dialysis Treatment on the Control of Interdialytic Weight Gain in Chronic Kidney Disease Patients on Dialysis (Stage 5D)

Aim of this study is to evaluate, in a population of chronic kidney disease patients on dialysis (Stage 5D), the effect of treatment with isonatremic dialysis (vs conventional dialysis), during an observational period of 2 months each, on:

• control of interdialytic weight gain
• perdialytic tolerance in terms of adverse events occurring during all of the sessions of the study
• body composition and thirst measured monthly during the 4 months of follow-up.
• tolerance to treatment.

Inclusion criteria:

• Chronic Kidney Disease patient on dialysis (stage 5D)
• With plasma sodium concentration between 130 and 140 mmol/L
• Anuric
• Patient dialysed with dialysis machine allowing isonatremic dialysis treatment

Exclusion criteria:

• Patient with plasma sodium concentration below 130 or above 140 mmol/
• Pacemaker