Biosignals by Wearables in Thyroid Dysfunction

Clinical Application of Continuous Monitoring Data for the Pulse Rate, Exercise, and Symptom Survey by Wearable Device in the Patients With Thyroid Dysfunction

This study is a single center observational study to investigate the association between biosignals from wearables and thyroid dysfunction.

An algorithm to predict thyroid dysfunction using heart rate and activity data from wearables was generated based on our previous clinical studies. This study was conducted to collect more data to advance the algorithm.

Patients with thyroid dysfunction including hypothyroidism and thyrotoxicosis were eligible for this study. During the study period, each subject wears a smart band (Fitbit Inspire 2 TM) and gets 3 times of thyroid function tests with 1-month interval. Study participants will use a mobile app (Glandy TM) to collect the symptom scores.

Inclusion Criteria:

• Subjects who were newly diagnosed as thyroid dysfunction (thyrotoxicosis or hypothyroidism) or undergoing treatment
• Subjects who are able to use wearable devices, smart phones, and mobile apps

Exclusion Criteria:

• Subjects with restrictions on normal activities due to diseases other than thyroid dysfunction
• Subjects who are taking medications affecting heart rate
• Subjects with diseases affecting heart rate (i.e. arrhythmia)