Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in fatiguing conditions. The current study investigates the effects of this supplementation in healthy males and females versus placebo on cognition, heart rate and perceived exertion, during a fatiguing cycling exercise.

Healthy males and females will be tested in fresh and fatiguing conditions to mimic individuals at the beginning or during a competition where cognitive function are important for decision making for example. Tests will be conducted during the warm-up (fresh), during fatiguing situations (during two consecutive 10-minutes pedaling exercises) and during recovery. Tests will include a reverse digit memory test (from 3 to 7 digits), a stroop test, a simple reaction time test. Moreover, heart rate and rating of perceived exertion will be quantified.

Inclusion Criteria:

• Body mass index lower than 27 and waist size lower than 94 cm
• physical activity higher than 3 hours a week
• written informed consent

Exclusion Criteria:

• more than 12 hours training a week
• asthmatic, smokers or under medicinal drugs
• dietary supplement, sports drink, special dietary food or functional food, of any kind, liable or presented as liable to enhance physical performances