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Sepsis is a syndrome involving infection and an abnormal systemic inflammatory response in the infected organism, resulting in organ dysfunction and possibly death. It is a major cause of hospital mortality. A large proportion of sepsis diagnoses are made in emergency departments. Early diagnosis and appropriate treatment have been shown to reduce mortality from this disease.
In a context of limited resources, it is therefore important to be able to quickly stratify patients presenting to the emergency department with a suspected infection into those who require rapid and intensive management because they are at risk of developing sepsis and septic shock and those who can be managed conventionally The objective of this study is to compare the clinical intuition of emergency room physicians and nurses with the qSOFA score to predict the clinical course of patients presenting to the emergency room with potential sepsis.
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| Measure | Description | Time Frame |
|---|---|---|
| Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 30-day mortality in patients with suspected infection | We compare the area under the ROC curve of each test (Emergency physicians' clinical intuition versus qSOFA score) to predict 30-day mortality in patients with suspected infection | 1 month after inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 72 hours mortality in patients with suspected infection | We compare the area under the ROC curve of each test (Emergency physicians' clinical intuition versus qSOFA score) to predict 72 hours mortality in patients with suspected infection | 72 hours after inclusion |
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Inclusion Criteria:
Temperature ≥ 38°C ou < 36°C measured in the emergency room Chills (in the emergency room or on recent history)
Exclusion Criteria:
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Patients presenting to one of the participating emergency departments with suspected infection
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Christelle JADEAU | Contact | 02 44 71 07 81 | cjadeau@ch-lemans.fr | |
| Adrien PICAUD | Contact | 02 43 43 43 43 | apicaud@ch-lemans.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Du Mans | Recruiting | Le Mans | 72000 | France |
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| ID | Term |
|---|---|
| D018805 | Sepsis |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |