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The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pharmaceutical intervention | Experimental | A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pharmaceutical intervention | Other | A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors deprescribe or introduce or remove prescribed drugs |
| Measure | Description | Time Frame |
|---|---|---|
| Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions | The acceptance of all pharmaceutical interventions related to inappropriate prescribed drugs and omission of prescription during the hospitalization of the patient will be evaluated, through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of polypharmacy in elderly people with cardiovascular diseases measured by prescription containing five or more drugs | First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year | |
| Incidence of omission of prescription drugs with proven efficacy for cardiovascular diseases measured by the START criteria |
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Inclusion Criteria:
Exclusion Criteria:
* Death
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Ana Nery | Salvador | Estado de Bahia | 40301-155 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41345711 | Derived | Gama RS, Passos LC, Amorim WW, Souza RM, Oliveira MG. Reducing Anticholinergic Burden in Hospitalised Older Adults: Analysis From the INFAR Study. Basic Clin Pharmacol Toxicol. 2026 Jan;138(1):e70160. doi: 10.1111/bcpt.70160. | |
| 40581959 | Derived | Gama RS, Passos LC, Amorim WW, Souza RM, Oliveira MG. Effectiveness of Pharmacist Interventions in Improving Medication Use in Hospitalised Older Patients Diagnosed With Cardiovascular Diseases: INFAR Before-and-After Study. J Eval Clin Pract. 2025 Jun;31(4):e70190. doi: 10.1111/jep.70190. |
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| First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year |
| Incidence of potentially inappropriate drug prescription in elderly people with cardiovascular diseases measured by the Beers criteria | First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year |