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Peripheral facial palsy is caused by damage to the facial nerve at any site of the peripheral branches after the facial nucleus.Stellate ganglion block is performed to treat peripheral facial palsy because it increases blood flow and promotes nerve regeneration.Facial Nerve Block worked with elimination of local inflammation of nerve and oppression. Facial nerve block is a treatment that inject drugs into the damaged nerve around to eliminate local inflammation and compression of the nerve.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Facial Nerve Block Group | Experimental | Facial Nerve Block and oral Mecobalamin Tablets |
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| Stellate Ganglion Block Group | Experimental | Facial Nerve Block and Stellate Ganglion Block and oral Mecobalamin Tablets |
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| D Group | Experimental | Facial Nerve Block |
|
| C Group | Other | control |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stellate Ganglion Block | Procedure | Patients underwent a stellate-ganglion block at the anterolateral aspect of the C6 vertebra. After local analgesia (lidocaine 2%), a 22-gauge Quincke needle was placed in the anterolateral aspect of the C6 vertebral body. When the needle contacted the bone, it was drawn back 1 mm. 5 mL of 0·5% ropivacaine was subsequently injected next to the stellate ganglion to produce a sympathetic block.The effect of the stellate-ganglion block on the sympathetic nervous system was confirmed by the presence of Horner's syndrome (ie, facial anhydrosis, enophthalmos, ptosis, swelling of the lower eyelid, miosis, and blood-shot conjunctiva), and an increase in the temperature of the right hand of at least 2°F from baseline. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline House-Brackmann | The House-Brackmann scale is a nerve grading system developed in 1985 by Los Angeles otolaryngologists Dr. John W. House and Dr. Derald E. Brackmann. It is used to characterize the severity of a facial paralysis patient's symptoms. | Baseline ,change from baseline House-Brackmann at 3 days,6 days,9 days,14 days,one month,two month |
| Change from Baseline Sunnybrook | Sunnybrook is a new facial nerve function of subjective assessment system.It is based on both static and dynamic aspects. | Baseline,change from baseline Sunnybrook at 3 days,6 days,9 days,14 days, one month,two month |
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Inclusion Criteria:
Diagnosed by clinical and neurological assessment as one-sided simple facial
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| zhuan zhang, professor | Yangzhou University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the Affiliated Hospital of Yangzhou University | Yangzhou | Jiangsu | China |
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| ID | Term |
|---|---|
| C019476 | mecobalamin |
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| Facial Nerve Block | Procedure | Operator touching the location of the mastoid, in the external auditory canal just below the front of the mastoid vertical needling.When touch the surface of the mastoid,adjust the needle across the front of the mastoid then slow needling about 1cm.The pin located below the stylomastoid foramen, and then injected drugs 5mL ( mecobalamin injection 1mg；lidocaine 60mg； dexamethasone 10mg ) |
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| Mecobalamin Tablets | Drug | oral Mecobalamin Tablets tid-8 |
|