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| Name | Class |
|---|---|
| Center for New Medical Technologies, Novosibirsk, Russia | OTHER |
| I.M. Sechenov First Moscow State Medical University | OTHER |
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A population-based case-cohort study of breast cancer-specific survival among all first invasive breast cancer cases
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CDSS (MedicBK) Analysis |
| ||
| Core Laboratory Analysis |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| neoadjuvant/adjuvant therapy | Drug | chemotherapy/endocrine therapy/surgery/radiotherapy |
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| Measure | Description | Time Frame |
|---|---|---|
| The percentage of guideline-consistent and personalized EBM recommendations | The percentage of guideline-consistent and personalized EBM recommendations acted on by clinicians in patients with first invasive breast cancer. All discrepancies between routine and CDSS-recommended treatment resulting in frame of guideline-consistent therapy and personalized EBM therapy will be adjudicated by core laboratory. | 3-year |
| Measure | Description | Time Frame |
|---|---|---|
| Breast cancer-specific survival | All deaths due to breast cancer-related causes | 3-year |
| Quantify the performance of the CDSS (MedicBK) algorithm | Quantify the performance of the CDSS (MedicBK) algorithm for presents treatment suggestions in frame of guideline-based therapy and personalized EBM therapy: the sensitivity, specificity, NPV, and PPV |
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Inclusion Criteria:
All women with stage I-III disease who survived at least 12 months post-diagnosis
Exclusion Criteria:
Unknown cause of death Treatment outside the region (thus precluding the treatment assessment)
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All first invasive breast cancer cases from a National Cancer Registry
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Evgeny Pokushalov, Prof. MD PhD | Contact | 89139254858 | e.pokushalov@gmail.com | |
| Irina Ostanina, MD | Contact | +79039031563 |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Evgeny Pokushalov | Recruiting | Novosibirsk | 630090 | Russia |
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| ID | Term |
|---|---|
| D020360 | Neoadjuvant Therapy |
| ID | Term |
|---|---|
| D003131 | Combined Modality Therapy |
| D013812 | Therapeutics |
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| 3-year |
| Predictors | Predictors of guideline-consistent and personalized EBM adherence | 3-year |