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Cancer patients have an increased risk of perioperative complications undergoing surgery procedures. Postoperative complications caused by thrombembolic events after robot- assisted surgery in major urological procedures have been reported and associated with an increased lenght of stay in the hospital. We therefore aimed to investigate in a retrospective analysis 250 patients undergoing robotic-assisted radical cystectomy and prostatectomy procedures for risk factors for thrombembolic events in this specific patient population.
Postoperative arterial or venous thrombembolism after robotic- assisted surgery in major urological procedures are reported severe complications in this patient population.
After having studied the available literature on this particular topic the investigators have decided to prepare a retrospective analysis of approximately 250 robot- assisted radical cystectomy and radical prostatectomy surgical procedures. In due consideration of perioperative prophylaxis of thrombembolic Events we determine the clinical and radiological signs of venous or arterial thrombembolism postoperatively with a particular focus on early postoperative pulmonary embolism events.
This is a retrospective analysis of 250 robotic-assisted radical cystectomy and radical prostatectomy surgical procedures.
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| Measure | Description | Time Frame |
|---|---|---|
| postoperative thrombembolism | Arterial and venous thrombembolism after surgery | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| acute renal failure | acute renal failure | through study completion, an average of 1 year |
| pulmonary oedema | pulmonary oedema | through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Collective of patients with bladder- and/or prostate cancer scheduled for laporoscopic robot-assited radical cystectomy and/or prostatectomy
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jochen Renner, Prof. Dr. | Contact | 004943150020801 | jochen.renner@uksh.de | |
| Ulf Lorenzen, Dr. | Contact | 004943150020801 | ulf.lorenzen@uksh.de |
| Name | Affiliation | Role |
|---|---|---|
| Jochen Renner, Prof. Dr. | University Hospital Schleswig-Holstein | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitätsklinikum Schleswig-Holstein | Recruiting | Kiel | Schleswig-Holstein | 24105 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24960494 | Background | Abel EJ, Wong K, Sado M, Leverson GE, Patel SR, Downs TM, Jarrard DF. Surgical operative time increases the risk of deep venous thrombosis and pulmonary embolism in robotic prostatectomy. JSLS. 2014 Apr-Jun;18(2):282-7. doi: 10.4293/108680813X13693422518551. | |
| 25443917 | Background | Mehrazin R, Piotrowski Z, Egleston B, Parker D, Tomaszweski JJ, Smaldone MC, Abbosh PH, Ito T, Bloch P, Iffrig K, Bilusic M, Chen DY, Viterbo R, Greenberg RE, Uzzo RG, Kutikov A. Is extended pharmacologic venous thromboembolism prophylaxis uniformly safe after radical cystectomy? Urology. 2014 Nov;84(5):1152-6. doi: 10.1016/j.urology.2014.06.058. Epub 2014 Oct 24. |
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| ID | Term |
|---|---|
| D014571 | Urologic Neoplasms |
| D013927 | Thrombosis |
| D004617 | Embolism |
| ID | Term |
|---|---|
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D052776 | Female Urogenital Diseases |
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| pneumonia | pneumonia | through study completion, an average of 1 year |
| wound infection | wound infection | through study completion, an average of 1 year |
| Major adverse cardiovascular events (MACE) | nonfatal stroke, nonfatal myocardial infarction and cardiovascular death | through study completion, an average of 1 year |
| ocular complications | ocular complications | through study completion, an average of 1 year |
| delirium | delirium | through study completion, an average of 1 year |
| 25158271 | Background | Tyritzis SI, Wallerstedt A, Steineck G, Nyberg T, Hugosson J, Bjartell A, Wilderang U, Thorsteinsdottir T, Carlsson S, Stranne J, Haglind E, Wiklund NP; LAPPRO Steering Committee. Thromboembolic complications in 3,544 patients undergoing radical prostatectomy with or without lymph node dissection. J Urol. 2015 Jan;193(1):117-25. doi: 10.1016/j.juro.2014.08.091. Epub 2014 Aug 23. |
| 18005777 | Background | Hope WW, Demeter BL, Newcomb WL, Schmelzer TM, Schiffern LM, Heniford BT, Sing RF. Postoperative pulmonary embolism: timing, diagnosis, treatment, and outcomes. Am J Surg. 2007 Dec;194(6):814-8; discussion 818-9. doi: 10.1016/j.amjsurg.2007.08.014. |
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D014570 | Urologic Diseases |
| D016769 | Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |