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Characterization of patients with long COVID syndrome including symptoms, medical history and persistent organ damage.
Some people are very hesitant to recover from a COVID-19 infection and present persistent symptoms. The participants still suffer after the acute phase of the infection from shortness of breath, coughing, chest pain or fatigue. Therefore, a special interdisciplinary consultation was built. The consulatation is not only addressed to people who have been hospitalized due to COVID-19, but also to those with mild symptoms during infection. During the consultation hours, personal health data are collected that serves as the basis for this research project.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Long COVID | Patients with long COVID syndrome |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other | no intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dyspnea | modified medical research council (scale from 0 to 4). The higher the score the worse the symptoms. | once through study completion, an average of 6 months. |
| self-addressed Quality of life | Short form health 36 questionnaire with 8 domains, each rated from 0-100. The higher the score the better subjective quality of life. | once through study completion, an average of 6 months |
| Thoracic pain | assessed by medical interview (reported as yes or no) | once through study completion, an average of 6 months |
| Medical history | List of relevant morbidities assessed as present/not present by medical interview (e.g. respiratory, cardial, neurological, psychiatric diseases by interview and medical records) | once through study completion, an average of 6 months |
| Fibrosis | Assessed by chest CT, rated as present/not present | once through study completion, an average of 6 months |
| Myocardial damage | Assessed by myocardial damage, rated as present/not present | once through study completion, an average of 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with long COVID syndrome
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| Name | Affiliation | Role |
|---|---|---|
| Christian F Clarenbach, MD | University Hospital Zurich, Pulmonology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Zurich | Zurich | Canton of Zurich | 8091 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37173355 | Derived | Malesevic S, Sievi NA, Baumgartner P, Roser K, Sommer G, Schmidt D, Vallelian F, Jelcic I, Clarenbach CF, Kohler M. Impaired health-related quality of life in long-COVID syndrome after mild to moderate COVID-19. Sci Rep. 2023 May 12;13(1):7717. doi: 10.1038/s41598-023-34678-8. |
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IPD will be shared on request
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| ID | Term |
|---|---|
| D000094024 | Post-Acute COVID-19 Syndrome |
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
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| D007239 |
| Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D000094025 | Post-Infectious Disorders |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |