Impact of FDG-PET/CT on Management of Patients with Native Valve Infective Endocarditis

Impact of FDG-PET/CT on Management of Patients with Native Valve Infective Endocarditis

The proposed study is a multicentric prospective observational cohort study of patients with suspected NVE. The study population includes those with Possible IE according to the modified Duke criteria and investigated at one of the 6 participating sites which include 2 cardiac centers, the MHI and the IUCPQ, as well as 4 tertiary care centers, the Jewish General Hospital , the McGill University Health Centre and the CHUS.

Inclusion Criteria:

• 18 years of age or older, capable to provide informed consent;
• Referred for a FDG-PET/CT study
• Classified as having Possible IE prior to FDG-PET/CT imaging;
• Patients must be able to tolerate the physical/logistical requirements of a PET/CT scan.

Exclusion Criteria:

• Subjects with prosthetic cardiac valve and/or CIED;
• Pregnant or breastfeeding female;
• Body mass index > 45 kg/m2.