Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations

Clinical Biocompatibility of Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations

The purpose of this study is to evaluate corneal staining observed after 2 hours of wear with an investigational contact lens against both PureVision contact lenses pre-cycled with Biotrue and Biofinity contact lenses pre-cycled with RepleniSH.

Subjects will be randomized in a 1:1:1:1 manner to receive one of 4 regimen sequences with lens and multipurpose disinfection solution (MPDS) combinations. The expected duration of subject participation in the study is approximately 1 week with 2 study visit days.

Key Inclusion Criteria:

• Understand and sign an Informed Consent;
• Successful wear of spherical soft contact lenses in both eyes for a minimum of 5 days per week and 8 hours per day during the past 3 months;
• Manifest cylinder of less than or equal to 1.50 diopter (D) in each eye;
• Best corrected visual acuity (BCVA) better than or equal to 20/25 Snellen in each eye;
• Willing to stop wearing habitual contact lenses for the duration of study lens exposure and during the washout period.
• Other protocol-specified inclusion criteria may apply.

Key Exclusion Criteria:

• Any eye condition or disease (including systemic) that contraindicates contact lens wear, as determined by the Investigator;
• Any use of systemic or ocular medications for which contact lens wear could be contraindicated, as determined by the Investigator;
• Eye surgery, as specified in the protocol;
• Dry eye; use of artificial tears, as specified in the protocol;
• Other protocol-specified exclusion criteria may apply.