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Comparison of the effectiveness of three methods of non-invasive ventilation in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery
The study includes the comparison of the three methods of non-invasive ventilation: non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery. It assumes 90 randomized patients:30 patients in three study groups male and female aged 30 to 60 years of age inclusive, with mild or moderate respiratory failure.The study will be randomized, single-center, prospective.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the first group: non-invasive mask ventilation | Experimental | Dinamika of the indicator p/F Ratio |
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| the second group:high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) | Experimental | Dinamika of the indicator p/F Ratio |
|
| the third group:non-invasive ventilation with a helmet | Experimental | Dinamika of the indicator p/F Ratio |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Using of non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet | Procedure | Using of non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet for tackling the problem of respiratory failure |
| Measure | Description | Time Frame |
|---|---|---|
| PaO2/FiO2 more than 300 | Comparison of PaO2/FiO2 before/after research | hospitalisation period, an average of 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| arterial blood oxygenation level | Comparison arterial blood oxygenation level before/after research | hospitalisation period, an average of 1 week |
| maximum inspiratory volume | Comparison maximum inspiratory volume before/after research |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alexander A. Eremenko, prof | Head of the Intensive Care Unit | Study Director |
| Darya V. Ryabova | anesthesiologist-resuscitator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Petrovsky Research National Centre of Surgery | Moscow | Russia |
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| Label | URL |
|---|---|
| The article | View source |
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|
| hospitalisation period, an average of 1 week |
| ID | Term |
|---|---|
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| D063087 | Noninvasive Ventilation |
| ID | Term |
|---|---|
| D012121 | Respiration, Artificial |
| D058109 | Airway Management |
| D013812 | Therapeutics |
| D012138 | Respiratory Therapy |
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