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Background:Knee osteoarthritis is more common in patients with type-2 diabetes mellitus, however it is not known whether this effect is caused by diabetes itself or concominant abdominal obesity.
Objectives:The aim of this study is to determine whether type-2 diabetes itself, independent of abdominal obesity, is a risk factor for femoral cartilage, knee osteoarthritis and poor quality of life.
Design:A cross-sectional design. Settings:Training and research hospital in Turkey. Patients and Methods:Female patients was enrolled in this study and divided into two groups: according to presence or absence of diabetes. Later, both the patients with and without abdominal obesity was divided into two groups according the presence of diabetes.
Main Outcome measures:Clinical parameters were visual analog-scale, gait speed and short form-36. Knee radiographs were evaluated according to Kellgren Lawrance-Scale. And ultrasonography parameters were the measurements of distal femoral cartilage thickness.
Sample size:126
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with type 2 diabetes | Experimental | Patients with diabetes mellitus was evaluated in terms of pain scores and ultrasonographic femoral cartilage thickness and retrospective radiographic knee osteoarthritis scores. |
|
| Patients without type 2 diabetes | Other | Patients without diabetes mellitus was evaluated in terms of pain scores and ultrasonographic femoral cartilage thickness and retrospective radiographic knee osteoarthritis scores. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| knee ultrasonography | Diagnostic Test | The knees of all patients were screened with ultrasonography device for the measurement of femoral cartilage thicknesses. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Femoral cartilage thickness | Measured by ultrasonography (higher value:thick cartilage, lower value:thin cartilage) | baseline |
| Measure | Description | Time Frame |
|---|---|---|
| visual analog scale | pain measurement (point 0 to 10) 0:worse pain 10:no pain | baseline |
| radiographic knee osteoarthritis | evaluated by kellgren lawrance scale.(0-4) 0:no osteoarthritis, 4: severe osteoarthritis |
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Inclusion Criteria:
Exclusion Criteria:
Knee osteoarthritis is more common in women.
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| Name | Affiliation | Role |
|---|---|---|
| Fulya Bakılan | Eskisehir City Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Eskişehir City Hospital | Eskişehir | Turkey (Türkiye) |
1 year later
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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Both patients with and without diabetes mellitus was evaluated in terms of pain and ultrasonographic femoral cartilage thickness.
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| baseline |
| D012216 |
| Rheumatic Diseases |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |