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| Name | Class |
|---|---|
| Hunan Province Tumor Hospital | OTHER |
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In advanced non-small cell lung cancer, there will be some rare mutations, such as ALK, KRAS, etc. The efficacy of these immunotherapies on these different rare mutations has not been reported. Therefore, we conducted this retrospective clinical study to explore the efficacy of immunotherapy for different rare mutations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| KRAS mutation | patients carry with KRAS mutation |
| |
| ALK fusion | patients carry with ALK fusion |
| |
| ERBB2 mutation | patients carry with ERBB2 mutation |
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| MET skipping/amplication | patients carry with MET skipping/amplication |
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| RET fusion | patients carry with RET fusion |
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| BRAF mutation | patients carry with BRAF mutation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| immunity therapy | Drug | The patient receives immunotherapy |
|
| Measure | Description | Time Frame |
|---|---|---|
| PFS | Defined as the time from the beginning of treatment to the first imaging disease progression or death (whichever occurs first) | January 2021- January 2021 (1 year) |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with advanced non-small-cell lung cancer carrying KRAS, ALK, ERBB2, MET, RET, BRAF mutation.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hunan Cancer Hospital | Recruiting | Changsha | Hunan | 410013 | China |
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| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
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| ID | Term |
|---|---|
| D007116 | Immunization, Passive |
| ID | Term |
|---|---|
| D007114 | Immunization |
| D007167 | Immunotherapy |
| D056747 | Immunomodulation |
| D001691 | Biological Therapy |
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| Hunan Cancer hospital | Recruiting | Changsha | Hunan | China |
|
| D013899 |
| Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D013812 |
| Therapeutics |
| D007158 | Immunologic Techniques |
| D008919 | Investigative Techniques |