Blood Loss and Preeclampsia

Does Preeclampsia Affect Blood Loss During a Caesarean Procedure

Study of blood loss in preeclamptic patients using mathematical formulae

Pre-eclampsia is a symptom complex that occurs in 2-5% of all pregnancies and leads to significant morbidity and mortality. It is associated with a risk of impaired coagulation caused by a reduced platelet count, very rarely by disseminated intravascular coagulation disorders. The degree of clotting correlates with the severity of preeclampsia. It is planned to calculate the blood loss using mathematical formulas and to compare the different blood loss in the two groups (preeclampsia vs. healthy pregnant women). Furthermore, this project will try to correlate the blood loss with the underlying coagulation situation. The aim is to be able to better assess the bleeding risk in healthy pregnant women, but also in pre-eclamptic patients in the future.

Inclusion Criteria:

• Elective or urgent caesarean section
• Written informed consent

Exclusion Criteria:

• Emergency caesarean section
• Familial coagulation disorder
• Hematological disorders that affect the platelet count, e.g. myelodysplastic syndrome (MDS)
• Taking anticoagulants
• Taking aspirin in the last 14 days
• Use of NSARs in the last 24 hours