Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 1R01DK116712-01A1 | U.S. NIH Grant/Contract | View source | |
| K24AG068601 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NIH |
| National Institute on Aging (NIA) | NIH |
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The parent trial that supports this ancillary research is a randomized controlled trial to evaluate the efficacy of a group-based yoga intervention to decrease the frequency and impact of urinary incontinence in ambulatory middle-aged and older women.
Women aged 45 years and older who report daily or more frequent stress-, urgency-, or mixed-type incontinence, are not already engaged in formal yoga or muscle stretching/strengthening programs, are willing to temporarily forgo other clinical treatments for incontinence, are able to walk to and use the bathroom without assistance, and meet other eligibility criteria are being recruited from multiple locations surrounding the San Francisco Bay area. Following a series of telephone- and then clinic-based screening assessments, including a voiding diary to confirm the frequency and clinical type of incontinence, eligible women are randomized in a 1:1 ratio to participate in either a 3-month yoga program (N~120) or a time-equivalent, non-specific muscle stretching and strengthening control program (N~120).
During the 3-month intervention period, participants participate in structured intervention programs (either yoga-specific or muscle stretching-strengthening) consisting of twice weekly, 90-minute group classes led by trained instructors). They are also be instructed to practice their assigned intervention for at least an additional hour per week, with the assistance of participant manuals created by the study team and a set of home yoga or stretching/strengthening exercise props.
For this ancillary trial research, the investigators are examining ancillary measures of a) physical performance status, b)perceived stress, depression, and anxiety symptoms, and c) sleep quality, duration, and continuity, already incorporated by the principal investigator into the parent trial. The investigators will examine prospective relationships between these ancillary measures and participant-reported urinary incontinence frequency/severity/impact, examine intervention effects on these ancillary outcomes, and assess the extent to which these ancillary outcomes mediate intervention effects on incontinence frequency/severity/impact.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoga Program | Experimental | The 3-month yoga intervention provides instruction and practice in a variety of yoga postures and techniques that have been selected by the study yoga expert consultants for their potential to improve bladder control and safety and feasibility for the target population. |
|
| Physical Conditioning Program | Active Comparator | The 3-month physical conditioning program provides instruction and practice in a variety of exercises and stretches that have been designed by the study physical therapist. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yoga Practice Program | Behavioral | 3 month group yoga classes |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in One-legged Balance Test (Winsorized) | Assess change in successive semi-tandem, tandem, and one-legged balance stand tests, in which their ability to hold each position for up to 30 seconds. Scoring is based on the number of seconds in which the participant is able to hold the one-legged balance position, ranging from 0 to 30. If a participant cannot make it through the semi-tandem and tandem stands, the one-legged balance will not be attempted. They will receive a score of zero for the one-legged balance. Change was calculated as the followup value minus the baseline value. Change values were Winsorized at the 1st and 99th percentile. Values are model generated Least Square Means for combined 6 and 12 week time points | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Chair Stands (in 30 Seconds) | Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. Higher score indicates better quality of life | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in 2-Minute Step Test | Assess change in aerobic endurance. In this test of aerobic endurance for older adults, participants are asked to step in place as many times as possible in a 2 minute period, each time raising the knee to a level midway between the patella and iliac crest. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points Higher scores indicating greater endurance. | Repeated change from baseline to 6 and 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Perceived Stress Scale (PSS) Score | Assess change in total score on Perceived Stress Scale (PSS), a 10-item measure of thoughts and feelings related to perceived stress in the past month, validated in a probability sample of the United States. Scores range from 0 to 40; higher scores indicated greater perceived stress. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alison Huang, MD, MAS | University of California, San Francisco | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California, San Francisco | San Francisco | California | 94143 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41359336 | Derived | Hough E, Goldstein LA, Subak LL, Chesney MA, Schembri M, Raghunathan H, Balys Pawlowsky S, Huang AJ. Effects of Hatha Yoga vs Physical Conditioning on Sleep in Women With Urinary Incontinence: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2025 Dec 1;8(12):e2546499. doi: 10.1001/jamanetworkopen.2025.46499. |
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| ID | Title | Description |
|---|---|---|
| FG000 | Yoga Program | The 3-month yoga intervention provides instruction and practice in a variety of yoga postures and techniques that have been selected by the study yoga expert consultants for their potential to improve bladder control and safety and feasibility for the target population. Yoga Practice Program: 3 month group yoga classes |
| FG001 | Physical Conditioning Program | The 3-month physical conditioning program provides instruction and practice in a variety of exercises and stretches that have been designed by the study physical therapist. Physical Conditioning Program: 3 month group physical conditioning classes |
| Title | Milestones | Reasons Not Completed | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
|
Not provided
Not provided
| ID | Title | Description |
|---|---|---|
| BG000 | Yoga Program | The 3-month yoga intervention provides instruction and practice in a variety of yoga postures and techniques that have been selected by the study yoga expert consultants for their potential to improve bladder control and safety and feasibility for the target population. Yoga Practice Program: 3 month group yoga classes |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Change From Baseline in One-legged Balance Test (Winsorized) | Assess change in successive semi-tandem, tandem, and one-legged balance stand tests, in which their ability to hold each position for up to 30 seconds. Scoring is based on the number of seconds in which the participant is able to hold the one-legged balance position, ranging from 0 to 30. If a participant cannot make it through the semi-tandem and tandem stands, the one-legged balance will not be attempted. They will receive a score of zero for the one-legged balance. Change was calculated as the followup value minus the baseline value. Change values were Winsorized at the 1st and 99th percentile. Values are model generated Least Square Means for combined 6 and 12 week time points | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | seconds | Repeated change from baseline to 6 and 12 weeks |
|
9 months
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Yoga Program | The 3-month yoga intervention provides instruction and practice in a variety of yoga postures and techniques that have been selected by the study yoga expert consultants for their potential to improve bladder control and safety and feasibility for the target population. Yoga Practice Program: 3 month group yoga classes |
| Term | Organ System | Source Vocabulary | Assessment Type | Notes | Statistical Information |
|---|---|---|---|---|---|
| Atrial Fibrillation | Cardiac disorders | MedDRA 22.1 | Systematic Assessment |
| Term | Organ System | Source Vocabulary | Assessment Type | Notes | Statistical Information |
|---|---|---|---|---|---|
| Recurrent Atrial Fibrillation | Cardiac disorders | MedDRA 22.1 | Non-systematic Assessment |
Not provided
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Alison Huang, MD, MAS, MPhil | University of California, San Francisco | 415-353-7900 | alison.huang@ucsf.edu |
Not provided
| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Mar 10, 2023 | Aug 1, 2023 | Prot_SAP_000.pdf |
Not provided
| ID | Term |
|---|---|
| D014549 | Urinary Incontinence |
| ID | Term |
|---|---|
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| Physical Conditioning Program |
| Behavioral |
3 month group physical conditioning classes |
|
| Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Center for Epidemiologic Studies Depression Scale (CES-D) | Assess change in total score on Center for Epidemiologic Studies Depression (CES-D) scale, a validated 20-item self-administered questionnaire measure that has been widely used in clinical trials, including trials of bladder interventions, and has been shown to be sensitive to change. Total scores range from 0 to 60, with higher scores indicate greater burden of depression symptoms. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in State/Trait Anxiety Inventory (STAI)--Trait | Assess change in somatic anxiety. Somatic anxiety (i.e., the affective component of anxiety believed to be related to autonomic physiological arousal response) is measured using the trait component of the Spielberger State Trait Anxiety Inventory (STAI), a 20-item self-administered measure validated in clinical populations, including patients with bladder symptoms. Scores range from 20 to 80, with higher scores indicating greater somatic anxiety. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Hospital Anxiety & Depression (HADS)--Anxiety Score | Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. Range 0-21, Higher score indicates lower quality of life | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Wake After Sleep Onset (Winsorized) | Assess change in sleep disruption. Average time spent awake after initial sleep onset is also assessed using the Pittsburgh Sleep Diary, based on participant recordings of nocturnal awakenings after initially falling asleep. Change was calculated as the followup value minus the baseline value. Change values were Winsorized at the 1st and 99th percentile. Values are model generated Least Square Means for combined 6 and 12 week time points. Higher score indicates lower quality of life. | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Pittsburgh Sleep Quality Index (PSQI) Total Score | Assess change in global sleep quality. Subjective sleep quality is being assessed using the Pittsburgh Sleep Quality Index (PSQI), an 18-item validated questionnaire originally designed to assess sleep quality, latency, efficiency, and problems over a one-week period. A global sleep quality score ranging from 0 to 21 can be derived from the PSQI, with higher scores reflecting poor sleep quality. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Repeated change from baseline to 6 and 12 weeks |
| Change From Baseline in Total Sleep Time | Assess change in average nightly sleep duration. Average total sleep duration is assessed using the Pittsburgh Sleep Diary is a daily self-report measure previously validated against actigraphy data, and used in multiple past studies of older adults. Change from baseline in Total sleep time. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. | Repeated change from baseline to 6 and 12 weeks |
| Serious Adverse Event |
|
| Too Busy |
|
| Lost to Follow-up |
|
| Family |
|
| No remote technology access |
|
| Withdrawal by Subject |
|
| Cannot tolerate intervention |
|
| Incomplete outcome data |
|
| BG001 |
| Physical Conditioning Program |
The 3-month physical conditioning program provides instruction and practice in a variety of exercises and stretches that have been designed by the study physical therapist. Physical Conditioning Program: 3 month group physical conditioning classes |
| BG002 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Race/Ethnicity, Customized | Count of Participants | Participants |
|
| Region of Enrollment | Count of Participants | Participants |
|
| Total Urinary Incontinence Episodes | Mean | Standard Deviation | episodes per day |
|
| Stress-Type Urinary Incontinence Episodes | Mean | Standard Deviation | episodes per day |
|
| Urgency-Type Urinary Incontinence Episodes | Mean | Standard Deviation | episodes per day |
|
| Incontinence Impact Questionnaire (IIQ) | Range 0-400, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| Urogenital distress inventory-6 score (UDI) | Range 0-100, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| Patient Perception of BladderCondition (PPBC) | Range 1-6, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| Center for Epidemiologic Studies Depression Scale (CES-D) | Range 0-60, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| State/Trait Anxiety Inventory (STAI)--Trait | Range 20-80, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| Hospital Anxiety & Depression (HADS)--Anxiety score | Range 0-21, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| Perceived Stress Scale (PSS) score | Range 0-40, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
| PROMIS Physical 8B, T-Score | (mean 50, Std Dev 10) no widely accepted thresholds have been published Higher score indicates better quality of life | Mean | Standard Deviation | T-score |
|
| One-legged Balance Test | Range 0-30, Higher score indicates better quality of life | Mean | Standard Deviation | seconds |
|
| Chair Stands (in 30 seconds) | Higher score indicates better quality of life | Mean | Standard Deviation | chair stands |
|
| 2-Minute Step Test | Higher score indicates better quality of life | Mean | Standard Deviation | steps |
|
| Wake after sleep onset | Higher score indicates lower quality of life | Mean | Standard Deviation | Minutes |
|
| Total sleep time | Higher score indicates better quality of life | Mean | Standard Deviation | hours |
|
| Pittsburgh Sleep Quality Index (PSQI) total score | Range 0-21, Higher score indicates lower quality of life | Mean | Standard Deviation | units on a scale |
|
The 3-month yoga intervention provides instruction and practice in a variety of yoga postures and techniques that have been selected by the study yoga expert consultants for their potential to improve bladder control and safety and feasibility for the target population.
Yoga Practice Program: 3 month group yoga classes
| OG001 | Physical Conditioning Program | The 3-month physical conditioning program provides instruction and practice in a variety of exercises and stretches that have been designed by the study physical therapist. Physical Conditioning Program: 3 month group physical conditioning classes |
|
|
|
| Primary | Change From Baseline in Chair Stands (in 30 Seconds) | Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. Higher score indicates better quality of life | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | chair stands | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Primary | Change From Baseline in 2-Minute Step Test | Assess change in aerobic endurance. In this test of aerobic endurance for older adults, participants are asked to step in place as many times as possible in a 2 minute period, each time raising the knee to a level midway between the patella and iliac crest. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points Higher scores indicating greater endurance. | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | steps | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Perceived Stress Scale (PSS) Score | Assess change in total score on Perceived Stress Scale (PSS), a 10-item measure of thoughts and feelings related to perceived stress in the past month, validated in a probability sample of the United States. Scores range from 0 to 40; higher scores indicated greater perceived stress. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | units on a scale | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Center for Epidemiologic Studies Depression Scale (CES-D) | Assess change in total score on Center for Epidemiologic Studies Depression (CES-D) scale, a validated 20-item self-administered questionnaire measure that has been widely used in clinical trials, including trials of bladder interventions, and has been shown to be sensitive to change. Total scores range from 0 to 60, with higher scores indicate greater burden of depression symptoms. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | units on a scale | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in State/Trait Anxiety Inventory (STAI)--Trait | Assess change in somatic anxiety. Somatic anxiety (i.e., the affective component of anxiety believed to be related to autonomic physiological arousal response) is measured using the trait component of the Spielberger State Trait Anxiety Inventory (STAI), a 20-item self-administered measure validated in clinical populations, including patients with bladder symptoms. Scores range from 20 to 80, with higher scores indicating greater somatic anxiety. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | score on a scale | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Hospital Anxiety & Depression (HADS)--Anxiety Score | Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. Range 0-21, Higher score indicates lower quality of life | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | units on a scale | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Wake After Sleep Onset (Winsorized) | Assess change in sleep disruption. Average time spent awake after initial sleep onset is also assessed using the Pittsburgh Sleep Diary, based on participant recordings of nocturnal awakenings after initially falling asleep. Change was calculated as the followup value minus the baseline value. Change values were Winsorized at the 1st and 99th percentile. Values are model generated Least Square Means for combined 6 and 12 week time points. Higher score indicates lower quality of life. | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | minutes | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Pittsburgh Sleep Quality Index (PSQI) Total Score | Assess change in global sleep quality. Subjective sleep quality is being assessed using the Pittsburgh Sleep Quality Index (PSQI), an 18-item validated questionnaire originally designed to assess sleep quality, latency, efficiency, and problems over a one-week period. A global sleep quality score ranging from 0 to 21 can be derived from the PSQI, with higher scores reflecting poor sleep quality. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | units on a scale | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| Secondary | Change From Baseline in Total Sleep Time | Assess change in average nightly sleep duration. Average total sleep duration is assessed using the Pittsburgh Sleep Diary is a daily self-report measure previously validated against actigraphy data, and used in multiple past studies of older adults. Change from baseline in Total sleep time. Change was calculated as the followup value minus the baseline value. Values are model generated Least Square Means for combined 6 and 12 week time points. | Number of participants with outcomes data | Posted | Least Squares Mean | 95% Confidence Interval | hours | Repeated change from baseline to 6 and 12 weeks |
|
|
|
|
| 0 |
| 121 |
| 1 |
| 121 |
| 37 |
| 121 |
| EG001 | Physical Conditioning Program | The 3-month physical conditioning program provides instruction and practice in a variety of exercises and stretches that have been designed by the study physical therapist. Physical Conditioning Program: 3 month group physical conditioning classes | 0 | 119 | 1 | 119 | 43 | 119 |
| High Grade B-Cell Lymphoma Burkitt-Like Lymphoma Nos | Neoplasms benign, malignant and unspecified (incl cysts and polyps) | MedDRA 22.1 | Systematic Assessment |
|
| Vertigo | Ear and labyrinth disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Detached Retina | Eye disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Abdominal Cramps | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Dental Discomfort | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Diarrhea | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Epigastric Pain | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Food Poisoning | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Tooth Pain | Gastrointestinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Facial Pain | General disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Allergy | Immune system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Allergy Nos | Immune system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Hay Fever | Immune system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Bladder Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Bronchitis | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Coronavirus Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Ear Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Lower Urinary Tract Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Mumps | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Shingles | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Tooth Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Upper Respiratory Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Urinary Tract Infection | Infections and infestations | MedDRA 22.1 | Non-systematic Assessment |
|
| Back Sprain | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Epicondylitis | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Fall | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Knee Injury | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Lateral Epicondylitis | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Leg Fracture | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Muscle Strain | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Pulled Hamstring | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Rib Fracture | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Shoulder Injury | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Toe Injury | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Vaccination Adverse Reaction | Injury, poisoning and procedural complications | MedDRA 22.1 | Non-systematic Assessment |
|
| Colonoscopy | Investigations | MedDRA 22.1 | Non-systematic Assessment |
|
| Endoscopy | Investigations | MedDRA 22.1 | Non-systematic Assessment |
|
| Back Muscle Spasms | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Back Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Back Pain; Knee Injury | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Foot Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Frozen Shoulder | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Groin Discomfort | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Hand Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Hip Arthrosis | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Hip Discomfort | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Knee Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Knee Swelling | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Leg Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Low Back Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Lumbar Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Muscle Soreness | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Neck Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Pain Ankle | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Pain In Ankle | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Pain In Elbow | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Pain In Hip | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Patellofemoral Pain Syndrome | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Rotator Cuff Injury | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Shoulder Deformity Nos | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Shoulder Pain | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Shoulder Soreness | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Spinal Disorder Nos | Musculoskeletal and connective tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Melanoma In Situ | Neoplasms benign, malignant and unspecified (incl cysts and polyps) | MedDRA 22.1 | Non-systematic Assessment |
|
| Cervical Radiculopathy | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Dizziness | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Headache | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Localised Numbness | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Migraine, Unspecified | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Neck Numbness | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Sciatica Aggravated | Nervous system disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Stress | Psychiatric disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Asthma Aggravated | Respiratory, thoracic and mediastinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Asthmatic Attack | Respiratory, thoracic and mediastinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Shortness Of Breath | Respiratory, thoracic and mediastinal disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Cyst Epidermal | Skin and subcutaneous tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Neck Rash | Skin and subcutaneous tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Rash | Skin and subcutaneous tissue disorders | MedDRA 22.1 | Non-systematic Assessment |
|
| Back Surgery | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Bladder Sling Procedure | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Bunionectomy | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Knee Arthroplasty | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Oral Surgery | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Shoulder Replacement | Surgical and medical procedures | MedDRA 22.1 | Non-systematic Assessment |
|
| Hot Flashes | Vascular disorders | MedDRA 22.1 | Non-systematic Assessment |
|
Not provided
Not provided
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |