The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

Inclusion Criteria:

• Decompensated liver cirrhosis ascetic patients.

Exclusion Criteria:

• Immunocompromised patients.
• Patients who had received antibiotics before hospital admission.
• Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs.
• Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.

Patients with ascites due to decompensated liver cirrhosis admitted at the inpatient section of Tropical Medicine and Gastroenterology Department, Sohag University Hospital.