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The study was withdrawn before enrollment due to administrative and board approval constraints.
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This is a plant-based medication used to increase the amount, protect, and reduce HIV's impact on T and B lymphocytes.
Dioscorea cirrhosa, impatiens balsamina, eclipta prostrata, phyllanthus urinaria, adenosma glutinosum, and ascorbic acid are used to elevate T and B lymphocytes level, protect their cells membrane, decrease the damage of HIV on CD4+ T.
In detail, Diosgenin presented in dioscorea cirrhosa is a precursor of cortisol. Dioscorea cirrhosa when combined with ascorbic acid helps to balance cortisol levels which reduces cell inflammation. Flavonoids of dioscorea cirrhosa also help to increase CD4+ T levels.
impatiens balsamina can be used as an antitoxin alternative against bacteria or viruses. Flavonoids in impatiens balsamina, such as kaempferol, quercetin, rutin, astragalin, have the ability to reduce the virus's impact on T lymphocyte, protect their cell membrane, produce antihistamine, protect the cell from inflammation.
Targeted flavonoids in eclipta prostrata, phyllanthus urinaria, adenosma glutinosum are used to cell repair, protect and increase CD4+ T production.
Ascorbic acid in combination with herbal extracts creates a favorable environment for body metabolism, improves the medication's effectiveness.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ahah drug | Experimental | Participants have a decline in CD4 + T-lymphocytes is the hallmark of the human immunodeficiency virus (HIV)-1 infection. Characterized by rapid loss of resistance: AIDS
Ahah composition contains the following ingredients (concentrated extracts of plants): Eclipta prostrata, dioscorea cirrhosa, phyllanthus urinaria, adenosma glutinosum, impatiens balsamina and ascorbic acid |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ahah Drug | Drug | - Composition Ahah containing concentrated extracts of plants: Eclipta prostrata, dioscorea cirrhosa, phyllanthus urinaria, adenosma glutinosum, impatiens balsamina and ascorbic acid. -Take 1tablet x 2 times / 24 hours. Maintained for 9 months. |
| Measure | Description | Time Frame |
|---|---|---|
| The CD4 cell count measurement | HIV is a fatal infection, characterized by the targeting and destruction of CD4 T lymphocytes in the peripheral blood. | - 9 months |
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Inclusion Criteria:
Characterized by rapid loss of resistance: AIDS
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tran Minh Duc, Dr. | Trieu, Nguyen Thi, M.D. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saigon Biopharma Company Limited | Ho Chi Minh City | 700000 | Vietnam |
| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
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| ID | Term |
|---|---|
| C113203 | A1A0 ATPase, Methanosarcina mazei |
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60 people were recruited HIV / AIDS positive between the ages of 20 and 60 and divided into 2 groups according to a random distribution.
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The group of HIV / AIDS uses drugs under study. The group of HIV / AIDS uses a placebo.
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|
| Ahah Placebo | Device | - Composition Ahah (not containing concentrated extracts of plants): Eclipta prostrata, dioscorea cirrhosa, phyllanthus urinaria, adenosma glutinosum, impatiens balsamina and ascorbic acid. -Take 1tablet x 2 times / 24 hours. Maintained for 9 months. |
|
|
| D015229 |
| Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |