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Cirrhosis registry of consecutive adult consenting patients hospitalized with liver cirrhosis in the tertiary liver unit
On admission to F.D.Roosevelt Teaching Hospital / HEGITO Liver Unit (Div Hepatology, Gastroenterology and Liver Transplant), all the adult patients with liver cirrhosis are offered to participate.
After providing informed consent, their demographic, clinical and laboratory / imaging data are uploaded by dedicated study person After discharge from the hospital, follow-up is recommended and uploaded to RH7 (if the follow-up visits take place at this institution [FDR]) Mortality data are uploaded from the national registry of dead on regular basis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adults with liver cirrhosis admitted to hospital liver unit | Consenting adults admitted with liver cirrhosis; recorded/uploaded are demographic, clinical, laboratory and imaging data |
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| Measure | Description | Time Frame |
|---|---|---|
| Frequency and type of decompensation of liver cirrhosis | Registrations reflect cirrhosis prevalence; decompensation are acute, chronic, or acute-on-chronic | "1 year" |
| Mortality | Record mortality in registered cirrhotics | "1 year" |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Record mortality in registered cirrhotics | 90-day |
| Mortality | Record mortality in registered cirrhotics | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Included are patients with liver cirrhosis and indication for hospital admission who are or are not candidates for liver transplant and have or do not have liver cancer
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lubomir Skladany, MD, PhD | Contact | +421905482997 | lubomir.skladany@gmail.com | |
| Janka Vnencakova, PhD | Contact | +421902160743 | janka.vnencakova1@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Lubomir Skladany, MD PhD | F.D.Roosevelt Teaching Hospital, Banska Bystrica, Slovakia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| F.D.Roosevelt Teaching Hospital | Recruiting | Banská Bystrica | 97401 | Slovakia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39031494 | Derived | Koller T, Vrbova P, Kubanek N, Zilincanova D, Selcanova SA, Havaj DJ, Skladany L. Assessment of intestinal inflammation via fecal calprotectin for early prediction of adverse outcomes in advanced chronic liver disease. United European Gastroenterol J. 2025 Apr;13(3):305-316. doi: 10.1002/ueg2.12633. Epub 2024 Jul 19. |
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Sharing by request primarily by investigators from other centres, editors of medical journals, authors of meta analyses, etc
On request, immediately, open ended
GDPR compliance Medical Journal Editorial office approved person Auditing authority Approved scientist
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| ID | Term |
|---|---|
| D008103 | Liver Cirrhosis |
| D000073496 | Frailty |
| D001201 | Ascites |
| D001927 | Brain Diseases |
| D007239 | Infections |
| D005355 | Fibrosis |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Data collection is at times enriched by stool samples collection for 16SRNA microbiome analysis
| Frailty | Measurement of the liver frailty index | On admission |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |