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The assessment of severity of the cognitive and functional impairment is essential in the follow-up of patients with neurocognitive disorders and in the assessment of the effectiveness of therapeutics. However, the systematic assessment of the Clinical Dementia Rating (CDR) scale is limited due to the time required to complete it (approximately 45 min to 1 hour). Insofar as studies have shown correspondences between the CDR and scales measuring cognitive and neuropsychological performance, and as part of memory consultations, several functional and neuropsychological scales are systematically administered, we wish to conduct a study validating the feasibility of the CDR based on information already available in the patient's file compared to the evaluation of the CDR by the usual method (face-to-face interview in consultation).
This study should highlight the feasibility of scoring the CDR-SB from the files of patients in memory consultation, first in terms of reliability of the scores obtained compared to the standard evaluation, and on the other hand in terms of organization and duration of administration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Memory consultation patient | The study will be conducted on the basis of the patient consulting in Memory Consultation, specifically with the information already collected in normal care and the MEMORA cohort. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CDR assessment face-to-face | Diagnostic Test | The assessment of the CDR is administered once by a psychologist with the patient and his caregiver. |
|
| Measure | Description | Time Frame |
|---|---|---|
| CDR Sum of boxes (CDR-SB) score out of 18 | The CDR-SB score is obtained in normal condition and on file for the same patients. The CDR-SB score makes it possible to distinguish the following classes: 0 (normal), 0.5-4 (questionable cognitive impairment), 0.5-2.5 (questionable impairment), 3-4 (very mild major TNC or very mild dementia), 4.5- 9 (mild or mild dementia), 9.5-15.5 (moderate dementia), 16-18 (severe dementia). The patient's aptitudes are assessed in 6 different areas: 3 cognitive skills: memory, orientation and judgment, 3 acts of everyday living: participation in collective life, home occupations and hobbies, personal care. | The CDR-SB score is collected at the baseline. |
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Inclusion Criteria:
Exclusion Criteria:
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The study will be conducted on the basis of the patient consulting in Memory Consultation, specifically with the information already collected in normal care and the MEMORA cohort.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anthony Bathsavanis, Psy D | Contact | 4 72 432 206 | +33 | anthony.bathsavanis@chu-lyon.fr |
| Virginie Dauphinot | Contact | virginie.dauphinot@chu-lyon.fr |
| Name | Affiliation | Role |
|---|---|---|
| Anthony Bathsavanis, Psy D | Hôpital des Charpennes | Study Director |
| Pierre Krolak-Salmon, MD | Hopital Edouard Herriot | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Des Charpennes | Recruiting | Villeurbanne | 69100 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39238042 | Derived | Dauphinot V, Calvi S, Moutet C, Xie J, Dautricourt S, Batsavanis A, Krolak-Salmon P, Garnier-Crussard A. Reliability of the assessment of the clinical dementia rating scale from the analysis of medical records in comparison with the reference method. Alzheimers Res Ther. 2024 Sep 5;16(1):198. doi: 10.1186/s13195-024-01567-9. |
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