STEP-IT-UP - Peanut Allergy Study for Infants

Subthreshold Peanut in Infants - Understanding Plasticity

Multicenter randomized (1:1) trial of strict avoidance versus sub-threshold dietary introduction of peanut in peanut allergic infants 4-14 months of age who react at a minimum cumulative dose of at least 430 mg of peanut protein at initial oral food challenge (OFC) for 12 months, followed by cross-over to sub-threshold dietary introduction of peanut in those randomized initially to avoidance.

Inclusion Criteria:

• Children age 4-14 months suspected to be peanut allergic

Exclusion Criteria:

• Significant medical problems