Role of Parasitic Infection in Inflammatory Bowel Disease and Irritable Bowel Syndrome

Role of Parasitic Infection in Inflammatory Bowel Disease and Irritable Bowel Syndrome

Role of parasitic infection in Inflammatory bowel disease and Irritable bowel The burden of the parasitic disease is in-direct relation with the health and nutritional status of the host, inducing not only parasite-specific immunity but also can modify the host's immune responses . Many parasites can imitate inflammatory bowel disorders and some studies showed that infection with parasites can improve disorders like IBD or moderate the symptoms of inflammatory bowel disorders . Even though, many studies have shown that gastrointestinal infection is an important risk factor for the development of IBS

1. Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.
2. Evaluating the effect of the parasite on the course and prognosis of the diseases.
3. Evaluating the effect of the antiparasitic drugs on the course and prognosis of the diseases.

Inclusion Criteria:

• Diagnosis of IBD will be confirmed using

  1. standard clinical,
  2. endoscopic,
  3. radiographic and4 pathological criteria according to the Montreal classification of the extent and severity of IBD

• Diagnosis of IBS will depend on Rome IV criteria

  1. Recurrent abdominal pain on average at least 1 day/week in the last 3 months,
  2. associated with two or more of the following criteria:
  3. Related to defecation;
  4. Associated with a change in the frequency of stool and/ or Associated with a change in the form (appearance) of stool.

Exclusion Criteria:

• any patient who received antipiotic or antiparasitic drug within the past 4 weeks