The aim of the study is to investigate the effects of 6 weeks of technological-assisted rehabilitation on function of upper extremity and hand in subjects with incomplete cervical spinal cord injury.

In this crossover study, persons with motor incomplete cervical (C2-C8) spinal cord injury (AIS C-D) will be recruited from the Hospital District of Helsinki and Uusimaa. In the first period of the crossover study, other part of the participants will get technological-assisted upper extremity rehabilitation, while the other part of the participants continue their normal lives. The first period is followed by 4-week wash-out period. In the second period, roles of the participants will be switched. The rehabilitation phase lasts for 6 weeks with 3 weekly sessions, each therapy session including at least 30 minutes of technological-assisted upper extremity rehabilitation. Rehabilitation includes passive, active and resistance exercises, and will be carried out by using AMADEO, PABLO and/or DIEGO devices made by Tyromotion.

Inclusion Criteria:

• incomplete motor spinal cord injury (AIS C-D)
• injury level C2-C8
• time since injury from 1 to 5 years
• to be able to sit
• motivation and ability to participate in intensive rehabilitation 3 times per week for 6 week period.

Exclusion Criteria:

• participation in other exercise study or technological-assisted upper extremity study
• unlikely completion of intervention and participation in follow up
• injuries that prevent training
• weak tolerance of intense training
• severe joint movement restriction or instability
• irreversible muscle contractures
• grade 4 on Modified Ashworth Scale in glenohumeral, elbow, wrist and finger joints
• recent significant forearm or hand injuries
• memory disorder
• orthopedic, rheumatic or neurological diseases (other than spinal cord injury) that prevent training