Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss

Local Tranexamic Acid During Vaginal Hysterectomy to Reduce Blood Loss

Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation

This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy.

The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; local 1gr tranexamic acid diluted in 10 ml saline and local 10 ml saline at the beginning of surgery.

Inclusion Criteria:

• 20-90 years old female patients going through vaginal hysterctomy

Exclusion Criteria:

• massive bleeding during operation due to major vessles injury
• known coagulopathies
• sensitivity to tranexamic acid
• medical need in tranexamic acid administration during operation due to bleeding