A Four Month Home Based tDCS Study on Patients With Alzheimer's Disease.

A Four Month Home Based tDCS Study on Patients With Alzheimer's Disease.

The study is an open label study on patients with Alzheimer's dementia using home based transcranial direct current (tDCS) stimulation. Aims of the study is to investigate applicability and effect of treatment.

Active tDCS of 2mA is applied via surface based electrodes daily for 30 minutes over a 4 month period. Anodal electrode is placed over the left temporal lobe. Participants is followed up by home visit and phone calls.

Cognitive tests are performed prior to the treatment period, right after finishing 4 months of treatment and 4 months after treatment is terminated.

Inclusion Criteria:

• Age 60-85.
• Fulfil diagnostic criteria of probable Alzheimer's dementia.
• Participants has to live with a caregiver.
• If medicated with cholinesterase inhibitors or memantine, a stable dose the last three months before inclusion is required.

Exclusion Criteria:

• Implant in head
• Seizure history
• Severe illness,
• Psychosis or depression measured with a cornell score over 11.
• Mini mental status (MMSE) score<17.