The aim of this study is to evaluate the clinical benefit and safety of using a computer aided detection device, Skout, for real-time polyp detection in colonoscopy procedures with the indication of screening or surveillance. One of the reasons for the development of interval colorectal cancers is polyps missed during colonoscopy. Our hypothesis is that with the aid of Skout, the adenomas detected per colonoscopy will increase, and it is plausible to believe that this increase in detection could reduce the incidence of interval cancers.

Inclusion Criteria

Participants will be eligible for this study if they are:

• Undergoing colonoscopy with screening, surveillance, or diagnostic indications.
• Undergoing a procedure by a participating endoscopist.
• Have given informed consent.

Exclusion Criteria

Participants will not be eligible for this study if they:

• Have a history of inflammatory bowel disease.
• Have a history of familial adenomatous polyposis.
• Are under the age of 40.
• Have had a colonoscopy within the previous three (3) years.
• Undergoing diagnostic colonoscopy with high-risk indications including iron deficiency anemia, abnormal CT imaging, unexplained weight loss, Lynch Syndrome, blood in stool or FIT positive test.
• Entered with poor bowel preparation (inadequate for procedure as assessed by the Investigator).
• Use anti-platelet agents or anticoagulants that preclude the removal of polyps during the procedure.