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The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with moderate impairment after a long-term use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BreEStim | Experimental | BreEStim is voluntary breathing controlled transcutaneous electrical nerve stimulation. |
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| EStim | Experimental | EStim is transcutaneous electrical nerve stimulation. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BreEStim | Device | BreEStim will be applied for 10 to 20 minutes per session for multiple sessions |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in finger flexor spasticity measured by Modified Ashworth Scale (MAS) | MAS will be performed to check changes of finger flexor spasticity after one session of treatment. The Modified Ashworth scale (MAS) scoring is categorical and ranges from 0 to 4, as follows: 0: No increase in muscle tone
| Baseline, after 10 intervention sessions, about 3 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in finger extensors and hand function measured by Fugl Myer Assessment (FMA) Scale | FMA will be assessed to test function changes of finger extensors and hand function after one session of treatment. The upper limb motor function domain of the FMA scale will be used, and the score range for this domain is 0 to 66, with a higher score indicating better function. | Baseline, after 10 intervention sessions, about 3 weeks |
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Inclusion criteria:
Exclusion criteria include:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sheng Li, MD, PhD | Contact | (713) 797-7125 | sheng.li@uth.tmc.edu | |
| Shengai Li, MS | Contact | 713-797-7561 | shengai.li@uth.tmc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Sheng Li, MD, PhD | University of Texas | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center | Recruiting | Houston | Texas | 77030 | United States |
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| EStim | Device | EStim will be applied for 10 to 20 minutes per session for multiple sessions |
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