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This study aims to evaluate whether IMA sparing may represent an advantage in terms of reduced incidence and severity of sexual dysfunctions after colorectal resections for diverticular disease (DD).
Enrolled patients were randomly divided into 2 treatment groups. In the first group (IMAP) the IMA was preserved sectioning the sigmoid arteries near colonic wall while, in the second group (IMAS) the IMA was sectioned immediately below the origin of the left colic artery. Incidence and severity of sexual dysfunction and QoL were assessed by four validated questionnaire administered 6,12 months and 5 and 8 years after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IMAP | Experimental | Inferior Mesenteric Artery Preservation Performing left hemicolectomy and anterior rectal resection the IMA was preserved ligating close to the colonic wall the sigmoids arteries. |
|
| IMAS | Active Comparator | Inferior Mesenteric Artery Ligation Performing left hemicolectomy the IMA is ligated and sectioned after the origin of left colic artery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Inferior Mesenteric Artery Preservation | Procedure | Performing left hemicolectomy the IMA was preserved ligating close to the colonic wall the sigmoids arteries. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sexual disfunction 1 | Presence of sexual disfunction ( defined through the evaluation of sexual desire ,arousal, lubrication , orgasmic function, overall satisfaction, pain, intercourse satisfaction , erectile function) | 12 months after surgery |
| Sexual disfunction 2 | Presence of sexual disfunction ( defined through the evaluation of sexual desire ,arousal, lubrication , orgasmic function, overall satisfaction, pain, intercourse satisfaction , erectile function) | 6 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Sexual Function Male 1 | assess the patients' sexual disorders with International Index of Erectile Function (IIEF) 15-items test | 12 month after surgery |
| Sexual Function Male 2 | assess the patients' sexual disorders with International Index of Erectile Function (IIEF) 15-items test |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Azienda Ospedaliera Sant'Andrea | Rome | 00188 | Italy |
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| Inferior Mesenteric Artery Ligation | Procedure | Performing left hemicolectomy the IMA is ligated and sectioned after the origin of left colic artery |
|
| 6 years after surgery |
| Sexual Function Female 1 | assess the patients' sexual disorders withFemale Sexual Function Index (FSFI) a 19-item test (score below 26.55 indicates the presence of sexual dysfunctions) | 12 months after surgery |
| Sexual Function Female 2 | assess the patient's sexual disorders with Female Sexual Function Index (FSFI) 19-item test (score below 26.55 indicates the presence of sexual dysfunctions) | 6 years after surgery |
| Quality of Life 1 | The impact of sexual disorders in QoL was evaluated using EORTC QLQ-30 ( European organisation for research and treatment of cancer- quality of life questionnaire) | 12 months after surgery |
| Quality of Life 2 | The impact of sexual disorders in QoL was evaluated using EORTC QLQ-30( European organisation for research and treatment of cancer- quality of life questionnaire) | 6 years after surgery |
| Quality of life SF-36 1 | The impact of sexual disorders in QoL was evaluated using SF-36 score (Short Form Health Survey 36) | 12 months after surgery |
| Quality of life SF-36 2 | The impact of sexual disorders in QoL was evaluated using SF- 36 score ( Short Form Health Survey 36 ) | 6 years after surgery |
| ID | Term |
|---|---|
| D020018 | Sexual Dysfunctions, Psychological |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
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