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The aim of the cohort prospective observational study is to define the major factors influencing the course of COVID-19 infections and its prognosis in hospitalised patients.
The investigators plan to include 300 patients hospitalised with COVID-19 infection.
The phone contacts with patients are due after 90 and 180 days after discharge.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chitotriosidase activity | Diagnostic Test | The chitotriosidase activity will be measured in all the subjects |
| Measure | Description | Time Frame |
|---|---|---|
| Need in biological therapy or/and respiratory support | The primary endpoint is the need in biological therapy or/and respiratory support including noninvasive ventilation during hospital stay | Up to 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Number of days spent in hospital | The investigators plan to assess the overall length of hospitalisation due to COVID-19 infection as an outcome measure | Up to 1 month |
| All-cause death | To assess the all-cause death 90 days after discharge |
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Inclusion Criteria:
Exclusion Criteria:
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300 patients hospitalised with COVID-19 infection
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| Name | Affiliation | Role |
|---|---|---|
| Olga Mironova, PhD | Sechenov University | Principal Investigator |
| Ekaterina Schelkanovtseva, MD | Sechenov University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital #1 | Moscow | Russia | ||||
| University Hospital #4 |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38159003 | Derived | Schelkanovtseva ES, Isaev GO, Mironova OY, Balakhonov AA, Skvortsov AV, Nagornov IO, Suvorov AY, Fomin VV, Panferov AS. [The survival prediction of hospitalized patients with COVID-19: the role of chitotriosidase level in peripheral blood]. Ter Arkh. 2023 Sep 29;95(7):543-547. doi: 10.26442/00403660.2023.07.202280. Russian. |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D045169 | Severe Acute Respiratory Syndrome |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| 90 days |
| All-cause death | To assess the all-cause death 180 days after discharge | 180 days |
| Moscow |
| Russia |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |