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| ID | Type | Description | Link |
|---|---|---|---|
| ID-RCB | Other Identifier | 2020-A01829-30 |
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Impossible to pursue the study
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Epilepsy is a neurological disease that can cause many comorbid psychiatric disorders, among them: generalized anxiety disorder and depression. Many studies suggest a temporal relationship between exposure to a traumatic event and the development of epilepsy. The objective of this research is to study the symptoms of post-traumatic stress disorder (PTS) in patients with epilepsy, and their relation to anxiety and depression in these patients. The investigators also wish to study how such symptoms may be associated with the subjective semiological manifestations of epileptic seizures. In addition, it has been shown that patients with epilepsy are able, from the identification of different warning signs, to anticipate their vulnerability to having an epileptic seizure allowing them to set up different types. strategies to control them. The investigators also wish to study the cognitive processes involved in this control and the influence of PTS symptoms, in particular hypervigilance on this behavior.
The investigators propose a protocol using different types of measures: emotional, cognitive and physiological in order to answer our questions. In addition to patients with epilepsy, two groups of patients will be included: a group of patients with another chronic non-neurological disease to compare the prevalence of PTS symptoms and a group of patients with post-traumatic stress disorder ( PTSD) to compare with patients with epilepsy, cognitive and physiological measures.
Finally, the results of this study should allow to develop tools for assessing PTS symptoms in epilepsy and to develop specific management approaches
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with epilepsy | Other |
| |
| Patients with PTSD | Other |
| |
| Patients with type 1 diabetes | Other |
| |
| Patients with a heart rhythm disorder | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Psycho-emotional and semiological measures | Other | Surveys, interviews and measures |
|
| Measure | Description | Time Frame |
|---|---|---|
| Anxiety level | Beck Anxiety inventory (0-63), higher values mean worse outcome | Baseline |
| Depression | Beck Anxiety inventory (0-21), higher values mean worse outcome | Baseline |
| Number of patients with PTSD | Post-traumatic stress disorder | Baseline |
| Emotion regulation | The difficulties in emotion regulation scale,(0-180), higher values mean better outcome | Baseline |
| Quality of life of the patient | Medical Outcome Study and 36-item Short Form Health Survey (0-60),higher values mean worse outcome | Baseline |
| Seizures control | Seizure control scale (0-85), higher values mean better outcome | Baseline |
| Seizures control (heart rythm) | HRSC | Baseline |
| PTSD | PTSD-E (0-100), higher values mean worse outcome | Baseline |
| Emotionnal control of diabete |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Olivier ARNAUD | Assistance Publique Hôpitaux de Marseille | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assistance Publique Hopitaux de Marseille | Marseille | 13354 | France |
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| ID | Term |
|---|---|
| D004827 | Epilepsy |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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DID-C (Diabete insulino-dependant-Control) (elaborated for the study) (0-150), higher values mean worse outcome |
| Baseline |
| Emotionnal control of diabete and PTSD | DID-PTSD (Diabete insulino-dependant-Posttraumatic Stress Disorder) (elaborated for the study) (0-185), higher values mean worse outcome | Baseline |
| Skin conductance | BIOPAC SCL (EDA 100C) | Baseline |
| Eyes movements | EyeLink 1000 (SR Research) | Baseline |
| Heart rythm variability | BIOPAC ECG (EL250) | Baseline |
| Attentional and executive control | Attentional and executive control task in the context of hypervigilance (elaborated for the study) (0-180), higher values mean worse outcome | Baseline |