The study has been designed in order to investigate the performance and safety of the new Silencia PD cycler including the Silencia tubing system in comparison to the PD-Night and Homechoice PD cycler which are both well-established PD cyclers.

Inclusion Criteria:

• Informed consent signed and dated by study patient and investigator/authorised physician
• CKD patients being treated with APD for at least 3 months
• Minimum age of 18 years
• Body weight ≥ 40 kg
• Fluid status regularly monitored with Body Composition Monitor (BCM)
• Patients planned to change to the Silencia PD cycler
• Proper functioning catheter
• Intraperitoneal Pressure (IPP) ≤ 18 cm H2O for the maximum of TAVO parameter "permitted patient volume"
• Ability to understand the nature and requirements of the study

Exclusion Criteria:

• Patients who have any condition prohibiting the use of BCM, like patients with major amputations (e.g. lower leg)
• Patients receiving polyglucose containing PD solution
• Any conditions which could interfere with the patient's ability to comply with the study
• Patients who suffer from peritonitis/exit site infection during the last 4 weeks
• Women of childbearing age without effective means of contraception, pregnancy (pregnancy test will be conducted at start and end of study) or lactation period
• Life expectancy < 3 months
• Participation in an interventional clinical study during the preceding 30 days
• Previous participation in the same study