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The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with demographic data.
For this study, which is planned as a cross-sectional clinical study, 100 patients who were diagnosed with AS between the ages of 18-65 and who applied to the Istanbul Physical Therapy Rehabilitation SUAM Physical Medicine and Rehabilitation Outpatient Clinic between April 15, 2019, and April 15, 2020, and 100 healthy volunteers compatible with age. was included. Demographic data of the participants were recorded. Work productivity and activity reduction questionnaire: general health (WPAI: GH), social role participation questionnaire short form (SRPQ), short form-36 (SF-36), hospital anxiety, and depression scale (HADS), will be evaluated. Besides, if the patient group exists, laboratory results (CRP, erythrocyte sedimentation rate, HLA-B27), and bath ankylosing spondylitis functional index (BASFI), bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis metrology index (BASMI), visual analog scale (VAS) resting, night and activity values were recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ankylosing Spondylitis | 100 patients who were diagnosed with AS between the ages of 18-65 | ||
| Healthy Volunteers | 100 healthy volunteers compatible with age. |
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| Measure | Description | Time Frame |
|---|---|---|
| Work Productivity and Activity Impairment Questionnaire: General Health V2.0 (WPAI:GH) | WPAI: GH measures health impact and symptom severity impact on work productivity and leave time effectiveness | One day |
| Social Role Participation Questionnaire (SRPQ) | It is used to evaluate integration into society and activities in social life. It evaluates the level of participation in six social roles in two dimensions: the "experienced physical difficulties scale" and the "role performance satisfaction scale". Participants complete their satisfaction and challenges during their social roles | One day |
| Measure | Description | Time Frame |
|---|---|---|
| Short Form Health Survey 36 (SF-36) | used to evaluate the quality of life | One day |
| Hospital Anxiety and Depression Scale (HADS) | used to determine the risk in terms of anxiety and depression in a patient with a physical illness, and to measure the level and change of severity. |
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Inclusion Criteria:
Exclusion Criteria:
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For this study, which is planned as a cross-sectional clinical study, 100 patients who were diagnosed with AS between the ages of 18-65 and who applied to the Istanbul Physical Therapy Rehabilitation SUAM Physical Medicine and Rehabilitation Outpatient Clinic between April 15, 2019, and April 15, 2020, and 100 healthy volunteers compatible with age was included.
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| Name | Affiliation | Role |
|---|---|---|
| Ömer Faruk Bucak, MD | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Derya Bugdayci, Assoc Prof | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30385702 | Background | Macfarlane GJ, Shim J, Jones GT, Walker-Bone K, Pathan E, Dean LE. Identifying Persons with Axial Spondyloarthritis At Risk of Poor Work Outcome: Results from the British Society for Rheumatology Biologics Register. J Rheumatol. 2019 Feb;46(2):145-152. doi: 10.3899/jrheum.180477. Epub 2018 Nov 1. | |
| 31576680 | Background |
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| ID | Term |
|---|---|
| D013167 | Spondylitis, Ankylosing |
| D013166 | Spondylitis |
| ID | Term |
|---|---|
| D000089183 | Axial Spondyloarthritis |
| D025242 | Spondylarthropathies |
| D025241 | Spondylarthritis |
| D013122 | Spinal Diseases |
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| One day |
| Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) | the assessment of disease activity in patients with ankylosing spondylitis | One day |
| Bath Ankylosing Spondylitis Functional Index (BASFI) | the assessment of functional status in patients with ankylosing spondylitis | One day |
| Bath Ankylosing Spondylitis Metrology Index (BASMI) | the assessment of the level of spinal mobility in patients with ankylosing spondylitis | One day |
| Ankylosing Spondylitis Quality of Life (ASQoL) | used to evaluate the quality of life in patients with ankylosing spondylitis | One day |
| Visual Analogue Scale (VAS) | used to evaluate the pain | One day |
| Goh Y, Kwan YH, Leung YY, Fong W, Cheung PP. A cross-sectional study on factors associated with poor work outcomes in patients with axial spondyloarthritis in Singapore. Int J Rheum Dis. 2019 Nov;22(11):2001-2008. doi: 10.1111/1756-185X.13696. Epub 2019 Oct 1. |
| 29504521 | Background | Sag S, Nas K, Sag MS, Tekeoglu I, Kamanli A. Relationship of work disability between the disease activity, depression and quality of life in patients with ankylosing spondylitis. J Back Musculoskelet Rehabil. 2018;31(3):499-505. doi: 10.3233/BMR-169657. |
| 29155961 | Background | van Lunteren M, Ez-Zaitouni Z, Fongen C, Landewe R, Ramonda R, van der Heijde D, van Gaalen FA. Disease activity decrease is associated with improvement in work productivity over 1 year in early axial spondyloarthritis (SPondyloArthritis Caught Early cohort). Rheumatology (Oxford). 2017 Dec 1;56(12):2222-2228. doi: 10.1093/rheumatology/kex365. |
| 27182067 | Background | Oude Voshaar M, van Onna M, van Genderen S, van de Laar M, van der Heijde D, Heuft L, Spoorenberg A, Luime J, Gignac M, Boonen A. Development and Validation of a Short Form of the Social Role Participation Questionnaire in Patients with Ankylosing Spondylitis. J Rheumatol. 2016 Jul;43(7):1386-92. doi: 10.3899/jrheum.151013. Epub 2016 May 15. |
| 27059161 | Background | van Genderen S, Plasqui G, Landewe R, Lacaille D, Arends S, van Gaalen F, van der Heijde D, Heuft L, Luime J, Spoorenberg A, Gignac M, Boonen A. Social Role Participation in Patients With Ankylosing Spondylitis: A Cross-Sectional Comparison With Population Controls. Arthritis Care Res (Hoboken). 2016 Dec;68(12):1899-1905. doi: 10.1002/acr.22907. Epub 2016 Oct 28. |
| 19685294 | Background | Cakar E, Taskaynatan MA, Dincer U, Kiralp MZ, Durmus O, Ozgul A. Work disability in ankylosing spondylitis: differences among working and work-disabled patients. Clin Rheumatol. 2009 Nov;28(11):1309-14. doi: 10.1007/s10067-009-1249-1. Epub 2009 Aug 16. |
| 19955052 | Background | Maksymowych WP, Gooch KL, Wong RL, Kupper H, van der Heijde D. Impact of age, sex, physical function, health-related quality of life, and treatment with adalimumab on work status and work productivity of patients with ankylosing spondylitis. J Rheumatol. 2010 Feb;37(2):385-92. doi: 10.3899/jrheum.090242. Epub 2009 Dec 1. |
| 27390130 | Background | Deodhar AA, Dougados M, Baeten DL, Cheng-Chung Wei J, Geusens P, Readie A, Richards HB, Martin R, Porter B. Effect of Secukinumab on Patient-Reported Outcomes in Patients With Active Ankylosing Spondylitis: A Phase III Randomized Trial (MEASURE 1). Arthritis Rheumatol. 2016 Dec;68(12):2901-2910. doi: 10.1002/art.39805. |
| D001847 |
| Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D000844 | Ankylosis |
| D007592 | Joint Diseases |
| D001168 | Arthritis |
| D001850 | Bone Diseases, Infectious |
| D007239 | Infections |